Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 8/20 | 0.86 |
| ▸ | PGR | P06401 | 7/20 | 0.86 |
| ▸ | ESR1 | P03372 | 6/20 | 0.86 |
| ▸ | AR | P10275 | 5/20 | 0.86 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.86 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.63 |
| ▸ | LMNA | P02545 | 5/20 | 0.63 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.63 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Etonogestrel SCHEMBL1649327 | 0.93 | SHBG (1.00) | SHBGPGRESR1AROPRM1 | |
| Etonogestrel SCHEMBL6462179 | 0.93 | SHBG (1.00) | SHBGPGRESR1AROPRM1 | |
| Etonogestrel SCHEMBL19510085 | 0.93 | SHBG (1.00) | SHBGPGRESR1AROPRM1 | |
| Etonogestrel SCHEMBL117703 | 0.93 | SHBG (1.00) | SHBGPGRESR1AROPRM1 | |
| Etonogestrel SCHEMBL484265 | 0.93 | SHBG (1.00) | SHBGPGRESR1AROPRM1 | |
| Etonogestrel SCHEMBL14946854 | 0.93 | SHBG (1.00) | SHBGPGRESR1AROPRM1 | |
| Etonogestrel SCHEMBL28648883 | 0.92 | SHBG (0.98) | SHBGPGRESR1AROPRM1 | |
| Etonogestrel SCHEMBL14941286 | 0.86 | SHBG (0.87) | SHBGPGRESR1AROPRM1 | |
| Etonogestrel SCHEMBL5729815 | 0.85 | SHBG (0.81) | SHBGPGRESR1AROPRM1 | |
| Etonogestrel SCHEMBL6150744 | 0.85 | SHBG (0.81) | SHBGPGRESR1AROPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11034716-B2 | Process and new intermediates for the preparation of 11-methylene steroids | CRYSTAL PHARMA, S.A.U. (ES) | 2021-06-15 | — | — | US | disclosed |
| US-20190092807-A1 | PROCESS AND NEW INTERMEDIATES FOR THE PREPARATION OF 11-METHYLENE STEROIDS | CURIA SPAIN, S.A.U. (ES) | 2019-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11034716-B2 | Process and new intermediates for the preparation of 11-methylene steroids | CYP17A1, HSD17B11, CYP19A1 | SHBG 25/4885PGR 38/4885ESR1 99/4885 |
| US-20190092807-A1 | PROCESS AND NEW INTERMEDIATES FOR THE PREPARATION OF 11-METHYLENE STEROIDS | CYP19A1, CYP17A1, HSD17B11 | SHBG 31/4885PGR 29/4885ESR1 79/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.