Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PDE6D | O43924 | 1/20 | 0.41 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20937290 | 0.89 | CCR2 (0.56) | CCR2KDM4EALDH1A1HTTESR1 | |
| SCHEMBL20853014 | 0.88 | ALDH1A1 (0.43) | CCR2HPGDKDM4EALDH1A1GAA | |
| SCHEMBL20853230 | 0.85 | PPARG (0.46) | CCR2HPGDKDM4EALDH1A1GAA | |
| SCHEMBL27764947 | 0.84 | CCR2 (0.49) | CCR2KDM4EALDH1A1KMT2A | |
| SCHEMBL20853252 | 0.84 | SRC (0.47) | CCR2HPGDKDM4EALDH1A1GAA | |
| SCHEMBL4797082 | 0.83 | CCR2 (0.58) | CCR2HPGDKDM4EALDH1A1GAA | |
| SCHEMBL27764949 | 0.83 | CCR2 (0.44) | CCR2KDM4EALDH1A1GAAHTT | |
| SCHEMBL27764615 | 0.83 | MIF (0.47) | HPGDALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL5365135 | 0.81 | CCR2 (0.51) | CCR2HPGDKDM4EALDH1A1GAA | |
| SCHEMBL5365133 | 0.81 | CCR2 (0.51) | CCR2HPGDKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019077631-A1 | IMIDAZO-PYRIDINE COMPOUNDS AS PAD INHIBITORS | JUBILANT BIOSYS LIMITED (IN) | 2019-04-25 | — | — | WO | disclosed |
| WO-2019058393-A1 | HETEROCYCLIC COMPOUNDS AS PAD INHIBITORS | JUBILANT BIOSYS LIMITED (IN) | 2019-03-28 | — | — | WO | disclosed |
| CN-101456840-B | Substituted tetrahydro carbazole derivates with optically | UNIV HUAZHONG NORMAL | 2011-05-11 | — | — | CN | disclosed |
| CN-101585801-A | Tetrahydrocarbazole compound and synthetic method thereof that the 3-indyl replaces | UNIV HUAZHONG NORMAL (CN) | 2009-11-25 | — | — | CN | disclosed |
| CN-101456840-A | Substituted tetrahydro carbazole derivates with optically activity and synthetic method thereof | UNIV HUAZHONG NORMAL (CN) | 2009-06-17 | — | — | CN | disclosed |