Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | TYMP | P19971 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphonic Acid SCHEMBL31096491 | 0.78 | CYP1A2 (0.46) | KDM4EALDH1A1HPGDALOX5AKR1C3 | |
| Phosphonic Acid SCHEMBL299962 | 0.78 | CYP1A2 (0.46) | KDM4EALDH1A1HPGDALOX5AKR1C3 | |
| SCHEMBL80143 | 0.77 | CYP1A2 (0.44) | KDM4EALDH1A1HPGDHDAC8PTPN1 | |
| SCHEMBL27874749 | 0.75 | ALOX5 (0.45) | KDM4EALDH1A1HPGDALOX5HDAC8 | |
| Alcohol SCHEMBL7737056 | 0.74 | PPARG (0.47) | ALDH1A1PPARGPPARAALOX5CNR2 | |
| SCHEMBL11615311 | 0.73 | IDO1 (0.48) | KDM4EALDH1A1HPGD | |
| Tetradecane SCHEMBL9931525 | 0.71 | CNR1 (0.51) | KDM4EALDH1A1HPGDCNR2GAA | |
| Decane SCHEMBL9931523 | 0.71 | CNR1 (0.51) | KDM4EALDH1A1HPGDCNR2GAA | |
| SCHEMBL11614578 | 0.71 | KMT2A (0.44) | KDM4EALDH1A1HPGDHDAC8GAA | |
| SCHEMBL2992860 | 0.70 | MEN1 (0.49) | KDM4EALDH1A1HPGDPTPN1ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3461556-A1 | PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS | AbbVie Ireland Unlimited Company (IE) | 2019-04-03 | — | — | EP | disclosed |