Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphonic Acid SCHEMBL31096491 | 1.00 | CYP1A2 (0.46) | CYP1A2KDM4EALDH1A1HPGDHDAC8 | |
| SCHEMBL27874749 | 0.91 | ALOX5 (0.45) | CYP1A2KDM4EALDH1A1HPGDHDAC8 | |
| SCHEMBL27953 | 0.84 | ALDH1A1 (0.59) | CYP1A2KDM4EALDH1A1HPGDPTPN1 | |
| SCHEMBL29350007 | 0.84 | ALDH1A1 (0.59) | CYP1A2KDM4EALDH1A1HPGDPTPN1 | |
| SCHEMBL25302086 | 0.84 | ALDH1A1 (0.59) | CYP1A2KDM4EALDH1A1HPGDPTPN1 | |
| Phosphoric Acid SCHEMBL547015 | 0.83 | ACP3 (0.55) | CYP1A2KDM4EALDH1A1HDAC8HDAC6 | |
| Phosphoric Acid SCHEMBL29911372 | 0.83 | ACP3 (0.55) | CYP1A2KDM4EALDH1A1HDAC8HDAC6 | |
| Bicarbonate SCHEMBL11569280 | 0.83 | NR4A1 (0.58) | CYP1A2KDM4EALDH1A1HPGDHDAC8 | |
| Phenanthrene SCHEMBL3811616 | 0.82 | ALDH1A1 (0.67) | CYP1A2ALDH1A1HPGDNR4A1NR4A2 | |
| SCHEMBL17836548 | 0.82 | ALDH1A1 (0.56) | CYP1A2KDM4EALDH1A1HPGDPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118751288-A | Preparation method of propenyl binaphthyl phosphonic acid/Pt-loaded hollow mesoporous nanospheres, product and application thereof | 重庆邮电大学 | 2024-10-11 | — | — | CN | claimed |
| CN-118751288-A | Preparation method of propenyl binaphthyl phosphonic acid/Pt-loaded hollow mesoporous nanospheres, product and application thereof | 重庆邮电大学 | 2024-10-11 | — | — | CN | disclosed |
| CN-118751288-A | Preparation method of propenyl binaphthyl phosphonic acid/Pt-loaded hollow mesoporous nanospheres, product and application thereof | 重庆邮电大学 | 2024-10-11 | — | — | CN | disclosed |
| CN-108084129-B | Method for synthesizing (1S, 5R) -lactone | 复旦大学 | 2022-09-16 | — | — | CN | disclosed |
| US-11441163-B2 | Enzyme-catalyzed synthesis of (1S,5R)-bicyclolactone | FUDAN UNIVERSITY (CN) | 2022-09-13 | — | — | US | disclosed |
| US-20210355516-A1 | ENZYME-CATALYZED SYNTHESIS OF (1S,5R)-BICYCLOLACTONE | FUDAN UNIVERSITY (CN) | 2021-11-18 | — | — | US | disclosed |
| US-10316012-B1 | Method of synthesizing (1S, 5R)-lactone | FUDAN UNIVERSITY (CN) | 2019-06-11 | — | — | US | disclosed |
| CN-108084129-A | （1S,5R）The synthetic method of-lactone | 复旦大学 | 2018-05-29 | — | — | CN | disclosed |
| EP-1888604-B1 | PROCESS FOR PREPARING (ALPHA S, BETA R)-6-BROMO-ALPHA-[2-(DIMETHYLAMINO)ETHYL]-2-METHOXY-ALPHA-1-NAPHTHALENYL-BETA-PHENYL-3-QUINOLINEETHANOL | JANSSEN PHARMACEUTICA NV (BE) | 2012-03-14 | — | — | EP | disclosed |
| EP-0451008-B1 | 8-Sulfamylmethylene-2-amino tetralins | MERRELL DOW PHARMA (US) | 1995-06-28 | — | — | EP | disclosed |
| EP-0451008-A1 | 8-Sulfamylmethylene-2-amino tetralins | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-10-09 | — | — | EP | disclosed |
| EP-0450238-A1 | Novel compounds for the treatment of migraine | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-10-09 | — | — | EP | disclosed |
| EP-0451022-A1 | Novel compounds for the treatment of migraine | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-10-09 | — | — | EP | disclosed |
| EP-0447727-A1 | Novel 8-sulfamylmethylene-2-amino tetralins | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-09-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10316012-B1 | Method of synthesizing (1S, 5R)-lactone | HAO2, HAO1, OXER1 | CYP1A2 216/4885KDM4E 3451/4885ALDH1A1 929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.