Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 2/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15037472 | 0.91 | NPC1 (0.36) | TDP1PSMD14ALDH1A1MEN1KMT2A | |
| SCHEMBL15037448 | 0.91 | NPC1 (0.36) | TDP1PSMD14ALDH1A1MEN1KMT2A | |
| SCHEMBL20853528 | 0.91 | NPC1 (0.36) | TDP1PSMD14ALDH1A1MEN1KMT2A | |
| SCHEMBL15018604 | 0.89 | CYP1A2 (0.32) | PSMD14KMT2ANPC1MAPTRAB9A | |
| SCHEMBL15018684 | 0.89 | CYP1A2 (0.32) | PSMD14KMT2ANPC1MAPTRAB9A | |
| SCHEMBL15037466 | 0.87 | ALDH1A1 (0.40) | TDP1GFERPSMD14ALDH1A1CYP3A4 | |
| SCHEMBL11585860 | 0.87 | ALDH1A1 (0.40) | TDP1GFERPSMD14ALDH1A1CYP3A4 | |
| SCHEMBL20853519 | 0.87 | CYP1A2 (0.30) | NPC1LMNAMAPTRAB9AGAA | |
| SCHEMBL16369064 | 0.87 | CYP1A2 (0.30) | NPC1LMNAMAPTRAB9AGAA | |
| SCHEMBL20853534 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791250-B1 | PARTICULAR AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH COMPOUND, IMPLEMENTATION PROCESS THEREFORE AND USE THEREOF | OREAL (FR) | 2019-04-03 | — | — | EP | disclosed |