Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Chloride SCHEMBL28823879 | 0.86 | LMNA (0.31) | LMNACA12CA1CA2CA3 | |
| Ethylene Glycol SCHEMBL4265688 | 0.86 | BRD4 (0.31) | LMNABRD4KDM4E | |
| SCHEMBL338264 | 0.85 | KDM4E (0.34) | ALDH1A1BRD4KDM4ECA12CA1 | |
| SCHEMBL1123 | 0.85 | — | — | |
| SCHEMBL785147 | 0.85 | — | — | |
| Ether SCHEMBL182700 | 0.82 | LMNA (0.37) | ALDH1A1LMNAKDM4E | |
| Propionic Acid SCHEMBL1518988 | 0.82 | FFAR3 (0.48) | ALDH1A1TSHRLMNACA12CA1 | |
| SCHEMBL23174460 | 0.82 | — | — | |
| SCHEMBL21409789 | 0.82 | — | — | |
| SCHEMBL21409686 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11801325-B2 | Tissue-adhesive polymers | POLYGANICS IP B.V. (NL) | 2023-10-31 | — | — | US | claimed |
| CN-111356485-B | Improved tissue adhesive polymers | 聚合物器官 IP 股份有限公司 | 2023-07-18 | — | — | CN | claimed |
| CN-115389757-A | Preparation method of fluorescence immunochromatographic test paper for multiple detection of silk fabrics and wool fabrics based on competition method | 浙江理工大学 | 2022-11-25 | — | — | CN | claimed |
| CN-115343465-A | Preparation method of fluorescence test paper for detecting silk fibroin based on double-antibody sandwich method | 浙江理工大学 | 2022-11-15 | — | — | CN | claimed |
| EP-3687588-B1 | TISSUE-ADHESIVE SEALANT DEVICE | POLYGANICS IP B V (NL) | 2022-07-20 | — | — | EP | claimed |
| US-11160900-B2 | Tissue-adhesive sealant device | POLYGANICS IP B.V. (NL) | 2021-11-02 | — | — | US | claimed |
| US-20200282103-A1 | Tissue-Adhesive Polymers | POLYGANICS IP B.V. (NL) | 2020-09-10 | — | — | US | claimed |
| US-20200261615-A1 | Tissue-Adhesive Sealant Device | POLYGANICS IP B.V. (NL) | 2020-08-20 | — | — | US | claimed |
| EP-3687589-A1 | IMPROVED TISSUE-ADHESIVE POLYMERS | Polyganics IP B.V. (NL) | 2020-08-05 | — | — | EP | claimed |
| CN-111372617-A | Tissue adhesive sealant device | 聚合物器官 IP 股份有限公司 | 2020-07-03 | — | — | CN | claimed |
| CN-111356485-A | Improved tissue adhesive polymers | 聚合物器官 IP 股份有限公司 | 2020-06-30 | — | — | CN | claimed |
| WO-2019066658-A1 | IMPROVED TISSUE-ADHESIVE POLYMERS | POLYGANICS IP B.V. (NL) | 2019-04-04 | — | — | WO | claimed |
| CN-108175857-A | For near infrared light excitation lower bismuth sulfide-zinc protoporphyrin composite material and preparation method and application with photodynamic therapy for cancer property | 中国科学院长春应用化学研究所 | 2018-06-19 | — | — | CN | claimed |
| US-11801325-B2 | Tissue-adhesive polymers | POLYGANICS IP B.V. (NL) | 2023-10-31 | — | — | US | disclosed |
| CN-111356485-B | Improved tissue adhesive polymers | 聚合物器官 IP 股份有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-111372617-B | Tissue adhesive sealant device | 聚合物器官 IP 股份有限公司 | 2023-02-17 | — | — | CN | disclosed |
| CN-111372617-A | Tissue adhesive sealant device | 聚合物器官 IP 股份有限公司 | 2020-07-03 | — | — | CN | disclosed |
| CN-111356485-A | Improved tissue adhesive polymers | 聚合物器官 IP 股份有限公司 | 2020-06-30 | — | — | CN | disclosed |
| WO-2019066658-A1 | IMPROVED TISSUE-ADHESIVE POLYMERS | POLYGANICS IP B.V. (NL) | 2019-04-04 | — | — | WO | disclosed |
| CN-108175857-A | For near infrared light excitation lower bismuth sulfide-zinc protoporphyrin composite material and preparation method and application with photodynamic therapy for cancer property | 中国科学院长春应用化学研究所 | 2018-06-19 | — | — | CN | disclosed |