Ether

Ether

SCHEMBL182700

CCOCC.O=C1CCC(=O)N1O

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.37
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
ALDH1A1 P00352 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propane SCHEMBL28183675 0.85 LMNA (0.33) LMNAKDM4E
Alcohol SCHEMBL20856433 0.82 ALDH1A1 (0.33) LMNAKDM4EALDH1A1
Ethyl Chloride SCHEMBL28823879 0.80 LMNA (0.31) LMNA
Methyl Alcohol SCHEMBL28183931 0.79 BRD4 (0.33) KDM4E
SCHEMBL338264 0.79 KDM4E (0.34) KDM4EALDH1A1
SCHEMBL1123 0.79
SCHEMBL785147 0.79
Ethyl Acetate SCHEMBL7351694 0.79 ALDH1A1 (0.56) LMNAKDM4EMEN1KMT2AALDH1A1
Pentane SCHEMBL28218834 0.78 FAAH (0.39) LMNAKDM4EKMT2AALDH1A1
Urethane SCHEMBL4882078 0.77 ALOX15 (0.58) LMNAKDM4EMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8389298-B2 Methods using novel chemiluminescent labels LUMIGEN, INC. (US) 2013-03-05 US claimed
US-20100190271-A1 METHODS USING NOVEL CHEMILUMINESCENT LABELS LUMIGEN, INC. (US) 2010-07-29 US claimed
US-20100173429-A1 METHODS USING NOVEL CHEMILUMINESCENT LABELS LUMIGEN, INC. (US) 2010-07-08 US claimed
US-20080113924-A1 Neuramindase Inhibitor NATIONAL INSTITUE OF ADVANCE INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2008-05-15 US claimed
US-20070172878-A1 Methods using novel chemiluminescent labels LUMIGEN, INC. 2007-07-26 US claimed
US-20060205094-A1 Methods using novel chemiluminescent labels LUMIGEN, INC. 2006-09-14 US claimed
US-RE49466-E1 Solution phase homogeneous assays BECKMAN COULTER, INC. (US) 2023-03-21 US disclosed
US-10603338-B2 Method for poly signal activation of apoptosis of malignant solid tumour cells OBSHESTVO S ORGANICHENNOI OTVETSTVENNOST'YU “BIOTEHNOLOGIYA” (RU) 2020-03-31 US disclosed
US-20180250331-A1 Method for Poly Signal Activation of Apoptosis of Malignant Solid Tumour Cells OBSHESTVO S OGRANICHENNOI OTVETSTVENNOST'YU "BIOTEHNOLOGIYA" (RU) 2018-09-06 US disclosed
EP-3354270-A1 METHOD FOR POLY SIGNAL ACTIVATION OF APOPTOSIS OF MALIGNANT SOLID TUMOUR CELLS Obshestvo S Ogranichennoi Otvetstvennost'yu "Biotehnologiya" (RU) 2018-08-01 EP disclosed
US-10036708-B2 Solution phase homogeneous assays BECKMAN COULTER, INC. (US) 2018-07-31 US disclosed
EP-2021778-B1 NONSEPARATION ASSAY METHODS BECKMAN COULTER INC (US) 2017-03-15 EP disclosed
EP-2027453-B1 NONSEPARATION ASSAY METHODS BECKMAN COULTER INC (US) 2017-03-15 EP disclosed
EP-2021778-A1 NONSEPARATION ASSAY METHODS Beckman Coulter, Inc. (US) 2009-02-11 EP disclosed
US-20080113924-A1 Neuramindase Inhibitor NATIONAL INSTITUE OF ADVANCE INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2008-05-15 US disclosed
WO-2007134098-A1 NONSEPARATION ASSAY METHODS BECKMAN COULTER, INC. (US) 2007-11-22 WO disclosed
WO-2007133988-A1 NONSEPARATION ASSAY METHODS BECKMAN COULTER, INC. (US) 2007-11-22 WO disclosed
US-20070264664-A1 Nonseparation assay methods NEXGEN DIAGNOSTICS LLC 2007-11-15 US disclosed
US-20070264665-A1 Nonseparation assay methods BECKMAN COULTER, INC. 2007-11-15 US disclosed
US-20060205094-A1 Methods using novel chemiluminescent labels LUMIGEN, INC. 2006-09-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080113924-A1 Neuramindase Inhibitor NMBR, NEU1, NMUR1 LMNA 3776/4885KDM4E 4523/4885MEN1 2118/4885
US-20070172878-A1 Methods using novel chemiluminescent labels HLCS, LANCL1, ACR LMNA 904/4885KDM4E 2463/4885MEN1 3342/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.