Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KARS1 | Q15046 | 4/20 | 0.69 |
| ▸ | RXRA | P19793 | 1/20 | 0.69 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.69 |
| ▸ | CDK2 | P24941 | 1/20 | 0.69 |
| ▸ | RXRB | P28702 | 1/20 | 0.69 |
| ▸ | RXRG | P48443 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.58 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.58 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.58 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL15389008 | 0.86 | KARS1 (0.57) | KARS1RXRACCNE1CDK2RXRB | |
| Fumaric Acid SCHEMBL2728217 | 0.86 | KARS1 (0.57) | KARS1RXRACCNE1CDK2RXRB | |
| Fumaric Acid SCHEMBL2728216 | 0.86 | KARS1 (0.57) | KARS1RXRACCNE1CDK2RXRB | |
| Fumaric Acid SCHEMBL2727847 | 0.86 | KARS1 (0.56) | KARS1RXRACCNE1CDK2RXRB | |
| Fumaric Acid SCHEMBL2727848 | 0.86 | KARS1 (0.56) | KARS1RXRACCNE1CDK2RXRB | |
| Fumaric Acid SCHEMBL2728615 | 0.86 | KARS1 (0.56) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietinal SCHEMBL2728308 | 0.85 | KARS1 (0.67) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietinal SCHEMBL20866441 | 0.85 | KARS1 (0.67) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietinal SCHEMBL2728310 | 0.85 | KARS1 (0.67) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietinal SCHEMBL13660121 | 0.85 | KARS1 (0.67) | KARS1RXRACCNE1CDK2RXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3687521-A1 | NEW DERIVATES OF DHAA WITH ELECTROSTATIC TUNING | Elinder, Fredrik (SE) | 2020-08-05 | — | — | EP | disclosed |
| US-20200239412-A1 | NEW DERIVATES OF DHAA WITH ELECTROSTATIC TUNING | ELINDER FREDRIK (SE) | 2020-07-30 | — | — | US | disclosed |
| US-20200239412-A1 | NEW DERIVATES OF DHAA WITH ELECTROSTATIC TUNING | ELINDER FREDRIK (SE) | 2020-07-30 | — | — | US | disclosed |
| WO-2019066711-A1 | NEW DERIVATES OF DHAA WITH ELECTROSTATIC TUNING | ELINDER FREDRIK (SE) | 2019-04-04 | — | — | WO | disclosed |
| WO-2019066711-A1 | NEW DERIVATES OF DHAA WITH ELECTROSTATIC TUNING | ELINDER FREDRIK (SE) | 2019-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200239412-A1 | NEW DERIVATES OF DHAA WITH ELECTROSTATIC TUNING | GRIN2B, ALOX15, GRIN2A | KARS1 3065/4885RXRA 1372/4885CCNE1 2460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.