Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 3/20 | 0.39 |
| ▸ | RORC | P51449 | 5/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.37 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10437098 | 0.80 | THRA (0.50) | TGM2SLC16A3THRATHRBPTPN1 | |
| SCHEMBL28738658 | 0.79 | THRA (0.56) | TGM2SLC16A3THRATHRBKMT2A | |
| SCHEMBL20856584 | 0.78 | TGM2 (0.46) | TGM2RORCFGFR4SLC16A3THRA | |
| Alcohol SCHEMBL20856541 | 0.78 | THRA (0.43) | TGM2RORCSLC16A3THRATHRB | |
| SCHEMBL27909138 | 0.78 | THRA (0.58) | SLC16A3THRATHRBKMT2ACYSLTR2 | |
| SCHEMBL28857062 | 0.76 | THRA (0.57) | SLC16A3THRATHRBKMT2ACYSLTR2 | |
| SCHEMBL28857121 | 0.76 | THRA (0.57) | SLC16A3THRATHRBKMT2ACYSLTR2 | |
| SCHEMBL28955038 | 0.76 | THRA (0.57) | SLC16A3THRATHRBKMT2ACYSLTR2 | |
| SCHEMBL28857136 | 0.76 | THRA (0.57) | SLC16A3THRATHRBKMT2ACYSLTR2 | |
| SCHEMBL28857158 | 0.76 | THRA (0.57) | SLC16A3THRATHRBKMT2ACYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019067396-A1 | ZAP-70 KINASE INHIBITOR COMPOSITIONS, METHODS AND USES THEREOF | SNAP BIO, INC. (US) | 2019-04-04 | — | — | WO | disclosed |