Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | PIKFYVE | Q9Y2I7 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13548879 | 0.86 | KDM5A (0.74) | KDM5AGAAKDM4ELMNAMAPT | |
| SCHEMBL13548880 | 0.78 | LMNA (0.60) | GAAKDM4ELMNAMAPTNPC1 | |
| SCHEMBL4411464 | 0.76 | GAA (0.72) | KDM5AGAAKDM4ELMNAMAPT | |
| SCHEMBL13548872 | 0.75 | GAA (0.70) | KDM5AGAAKDM4ELMNAMAPT | |
| SCHEMBL21711070 | 0.74 | KDM5A (0.78) | KDM5AGAAKDM4ELMNAMAPT | |
| SCHEMBL19519006 | 0.73 | KDM5A (0.42) | KDM5AGAAKDM4EMAPTNPC1 | |
| SCHEMBL4407764 | 0.73 | PIKFYVE (0.61) | KDM5AGAAKDM4ELMNAMAPT | |
| SCHEMBL13548869 | 0.73 | KDM5A (0.70) | KDM5AGAAKDM4ELMNAMAPT | |
| SCHEMBL4411519 | 0.72 | KDM5A (1.00) | KDM5AGAAKDM4ELMNAMAPT | |
| SCHEMBL13548881 | 0.72 | KDM5A (0.78) | KDM5AGAAKDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3461813-A1 | THERAMUTEIN MODULATORS | Housey, Gerard M. (US) | 2019-04-03 | — | — | EP | disclosed |