Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.58 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.58 |
| ▸ | TAS1R2 | Q8TE23 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.31 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL702097 | 0.74 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2ALDH1A1HSD17B10 | |
| SCHEMBL702741 | 0.70 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2ALDH1A1HSD17B10 | |
| SCHEMBL29412432 | 0.70 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2ALDH1A1HSD17B10 | |
| SCHEMBL702742 | 0.70 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2ALDH1A1HSD17B10 | |
| SCHEMBL5317303 | 0.69 | TAS1R3 (0.79) | TAS1R3TAS1R1TAS1R2ALDH1A1HSD17B10 | |
| SCHEMBL5317302 | 0.69 | TAS1R3 (0.79) | TAS1R3TAS1R1TAS1R2ALDH1A1HSD17B10 | |
| SCHEMBL20860977 | 0.67 | TAS1R3 (0.64) | TAS1R3TAS1R1TAS1R2ALDH1A1HSD17B10 | |
| SCHEMBL702397 | 0.67 | TAS1R3 (0.64) | TAS1R3TAS1R1TAS1R2ALDH1A1HSD17B10 | |
| SCHEMBL5277236 | 0.67 | TAS1R3 (0.64) | TAS1R3TAS1R1TAS1R2ALDH1A1HSD17B10 | |
| SCHEMBL701644 | 0.65 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1659881-B1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | SENOMYX INC (US) | 2019-04-03 | — | — | EP | disclosed |