Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 3/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23486491 | 0.81 | HDAC1 (0.50) | CLK1DYRK1ADYRK1BHDAC1 | |
| SCHEMBL24114706 | 0.81 | CLK1 (0.41) | CLK1DYRK1ADYRK1BKMT2AMEN1 | |
| SCHEMBL2895956 | 0.80 | KMT2A (0.61) | CLK1DYRK1ADYRK1BKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9432010 | 0.78 | F9 (0.56) | — | |
| SCHEMBL21417393 | 0.76 | PTPN2 (0.50) | CLK1DYRK1ADYRK1BKMT2AMEN1 | |
| SCHEMBL9623048 | 0.73 | CLK1 (0.60) | CLK1DYRK1ADYRK1BCA2 | |
| SCHEMBL9622778 | 0.73 | BCL2L1 (0.58) | DYRK1AHDAC1CYP2A6RAB9AL3MBTL1 | |
| SCHEMBL10222545 | 0.73 | CYP2A6 (0.45) | KMT2AMEN1CYP1A2CYP2A6RAB9A | |
| SCHEMBL8171694 | 0.73 | CYP2A6 (0.45) | KMT2AMEN1CYP1A2CYP2A6RAB9A | |
| SCHEMBL17400987 | 0.72 | CYP2A6 (0.44) | KMT2AMEN1CYP1A2CYP2A6RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1659881-B1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | SENOMYX INC (US) | 2019-04-03 | — | — | EP | disclosed |