Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 18/20 | 0.60 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.60 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.60 |
| ▸ | BACE1 | P56817 | 1/20 | 0.56 |
| ▸ | CLK2 | P49760 | 4/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599424 | 0.87 | CA2 (0.49) | CLK1DYRK1ADYRK1BBACE1CA2 | |
| SCHEMBL1867721 | 0.80 | CLK1 (0.68) | CLK1DYRK1ADYRK1BBACE1CLK2 | |
| SCHEMBL13709491 | 0.79 | F9 (0.65) | CLK1DYRK1ADYRK1BBACE1CLK2 | |
| SCHEMBL2138351 | 0.79 | CLK1 (0.67) | CLK1DYRK1ADYRK1BCLK2CLK4 | |
| SCHEMBL19756734 | 0.79 | CLK1 (0.67) | CLK1DYRK1ADYRK1BBACE1CLK2 | |
| SCHEMBL7340422 | 0.79 | CLK1 (0.67) | CLK1DYRK1ADYRK1BBACE1CLK2 | |
| SCHEMBL5546367 | 0.75 | BACE1 (0.62) | CLK1DYRK1ADYRK1BBACE1CLK2 | |
| SCHEMBL10238993 | 0.75 | CLK1 (1.00) | CLK1DYRK1ADYRK1BCLK2CLK4 | |
| SCHEMBL4580171 | 0.74 | BACE1 (0.67) | CLK1DYRK1ADYRK1BBACE1CLK2 | |
| SCHEMBL1391285 | 0.74 | CLK1 (0.60) | CLK1DYRK1ADYRK1BCLK2CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166204-A | ISOINDOLE DERIVATIVES AND SALTS THEREOF AND ANTITUMOR AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1992-11-24 | — | — | US | disclosed |