Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.76 |
| ▸ | MEN1 | O00255 | 5/20 | 0.76 |
| ▸ | RAB9A | P51151 | 5/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.52 |
| ▸ | KDR | P35968 | 2/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6724021 | 0.87 | KMT2A (0.78) | KMT2AMEN1RAB9ANPC1KDM4E | |
| Hydrochloric Acid SCHEMBL7203895 | 0.86 | KMT2A (0.76) | KMT2AMEN1RAB9ANPC1KDM4E | |
| SCHEMBL6568502 | 0.82 | RAB9A (0.68) | KMT2AMEN1RAB9AKDM4EMAPT | |
| SCHEMBL17929424 | 0.81 | PDGFRB (0.55) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL1276481 | 0.80 | KDM4E (0.82) | KMT2AMEN1RAB9ANPC1KDM4E | |
| SCHEMBL30393282 | 0.80 | KDM4E (0.82) | KMT2AMEN1RAB9ANPC1KDM4E | |
| SCHEMBL31328460 | 0.80 | RAB9A (0.70) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL11052575 | 0.80 | RAB9A (1.00) | KMT2AMEN1RAB9ANPC1KDM4E | |
| SCHEMBL4345368 | 0.77 | RAB9A (0.65) | KMT2AMEN1RAB9ANPC1KDM4E | |
| SCHEMBL6724026 | 0.76 | SIGMAR1 (0.63) | KMT2AMEN1RAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3050881-B1 | NOVEL A-NAPHTHYLUREA DERIVATIVE AND MEDICAL APPLICATION OF THE SAME IN THE TREATMENT OF VISUAL LOSS AND CANCER DISEASES | SUZHOU RAYMON PHARMACEUTICALS COMPANY LTD (CN) | 2019-04-03 | — | — | EP | disclosed |