Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL227352 | 0.88 | CES2 (0.55) | CES2CES1HDAC4HDAC7HDAC5 | |
| SCHEMBL30903827 | 0.85 | CES2 (0.53) | CES2CES1ADAM17 | |
| SCHEMBL3897101 | 0.85 | CES2 (0.53) | CES2CES1ADAM17 | |
| SCHEMBL230519 | 0.84 | CES2 (0.49) | CES2CES1HDAC4HDAC7HDAC5 | |
| SCHEMBL231190 | 0.84 | CES2 (0.46) | CES2CES1ADAM17SLC6A2SLC6A4 | |
| SCHEMBL17235718 | 0.84 | HDAC4 (0.44) | CES2CES1HDAC4HDAC7HDAC5 | |
| SCHEMBL6349980 | 0.83 | CES2 (0.45) | CES2CES1HDAC4HDAC7HDAC5 | |
| SCHEMBL230516 | 0.82 | CES2 (0.50) | CES2CES1HDAC4HDAC7HDAC5 | |
| SCHEMBL230487 | 0.82 | IDO1 (0.52) | CES2CES1HDAC4HDAC7HDAC5 | |
| SCHEMBL230488 | 0.81 | OPRM1 (0.47) | CES2CES1HDAC4HDAC7HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3112337-B1 | LIQUID CRYSTALLINE COMPOUND CONTAINING TETRAFLUOROFLUORENE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORP (JP) | 2019-04-03 | — | — | EP | disclosed |