⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30695162 | 0.71 | KMT2A (0.44) | — | |
| SCHEMBL21465403 | 0.70 | KMT2A (0.43) | — | |
| Lithium SCHEMBL31401899 | 0.69 | JMJD6 (0.42) | — | |
| SCHEMBL1630090 | 0.69 | — | — | |
| SCHEMBL324166 | 0.69 | — | — | |
| SCHEMBL30463448 | 0.68 | KDM4E (0.44) | — | |
| SCHEMBL31277599 | 0.68 | JMJD6 (0.49) | — | |
| SCHEMBL350714 | 0.67 | — | — | |
| SCHEMBL6183796 | 0.67 | — | — | |
| SCHEMBL20892184 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 499 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140294763-A1 | PEPTIDOMIMETIC PROTEASE INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED | 2014-10-02 | — | — | US | claimed |
| EP-2368877-B1 | Peptidomimetic protease inhibitors and intermediates for their preparation As treatment for HCV infection | VERTEX PHARMA (US) | 2014-05-07 | — | — | EP | claimed |
| EP-1958956-B1 | Peptidomimetic protease inhibitors | VERTEX PHARMA (US) | 2013-12-11 | — | — | EP | claimed |
| US-20120282219-A1 | PEPTIDOMIMETIC PROTEASE INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-11-08 | — | — | US | claimed |
| US-8252923-B2 | Peptidomimetic protease inhibitors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-08-28 | — | — | US | claimed |
| CN-102504014-A | Peptidomimetic protease inhibitors | LILLY CO ELI | 2012-06-20 | — | — | CN | claimed |
| EP-1990343-B1 | Azaindoles | AVENTIS PHARMA LTD (GB) | 2012-04-04 | — | — | EP | claimed |
| US-20120064034-A1 | Peptidomimetic protease inhibitors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-03-15 | — | — | US | claimed |
| EP-2368901-A1 | Peptidomimetic protease inhibitors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-09-28 | — | — | EP | claimed |
| EP-2368877-A1 | Chiral intermediates for the preparation of peptidomimetic protease inhibitors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-09-28 | — | — | EP | claimed |
| EP-1778228-A2 | THERAPEUTIC COMPOUND AND TREATMENTS | Medisyn Technologies, Inc. (US) | 2007-05-02 | — | — | EP | claimed |
| EP-1027328-B1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LTD (GB) | 2006-08-23 | — | — | EP | claimed |
| WO-2006010127-A2 | THERAPEUTIC COMPOUND AND TREATMENTS | MEDISYN TECHNOLOGIES, INC. (US) | 2006-01-26 | — | — | WO | claimed |
| US-20060014770-A1 | Inhibiting cell growth including cancer such as leukemia, melanoma, cancer of non-small cell lung, colon , CNS, ovarian , renal , prostate , breast , and pancreas | COUSINEAU, HENRY | 2006-01-19 | — | — | US | claimed |
| US-20050197299-A1 | Hepatitis C antiviral agents including telaprevir (VX 950); higher tolerance, reduced side effects; azaheterocyclic amido ketone derivatives | VERTEX PHARMACEUTICALS INCORPORATED | 2005-09-08 | — | — | US | claimed |
| EP-0960096-B1 | SUBSTITUTED BETA-THIOCARBOXYLIC ACIDS | AVENTIS PHARMA INC (US) | 2005-04-06 | — | — | EP | claimed |
| EP-1486486-A2 | Substituted B-thiocarboxylic acids | Aventis Pharmaceuticals Inc. (US) | 2004-12-15 | — | — | EP | claimed |
| EP-1189883-B1 | SUBSTITUTED PYRROLIDINES AS CELL ADHESION INHIBITORS | AVENTIS PHARMA LTD (GB) | 2004-11-03 | — | — | EP | claimed |
| EP-1259495-B1 | INDANE DERIVATIVES AND THEIR USE AS CELL ADHESION INHIBITORS | AVENTIS PHARMA LTD (GB) | 2004-09-22 | — | — | EP | claimed |
| EP-1140916-B1 | HETEROARYL-CYCLIC ACETALS | AVENTIS PHARMA LTD (GB) | 2002-11-13 | — | — | EP | claimed |