Lithium

Lithium

SCHEMBL31401899

Cn1ccc(-c2nc(O)cc(O)n2)n1.[Li]

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
JMJD6 Q6NYC1 12/20 0.42
KMT2A Q03164 1/20 0.42
KEAP1 Q14145 1/20 0.40
KDM4E B2RXH2 1/20 0.39
MKNK1 Q9BUB5 1/20 0.38
MKNK2 Q9HBH9 1/20 0.38
PIK3CD O00329 1/20 0.36
PIP5K1C O60331 1/20 0.36
PIK3CA P42336 1/20 0.36
PIK3CB P42338 1/20 0.36
PI4KA P42356 1/20 0.36
PIK3CG P48736 1/20 0.36
PI4KB Q9UBF8 1/20 0.36
KDM5B Q9UGL1 1/20 0.36
SCN4A P35499 1/20 0.34
CYP19A1 P11511 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30695162 0.98 KMT2A (0.44) JMJD6KMT2AKEAP1KDM4EMKNK1
Lithium Ion SCHEMBL31561400 0.84 JMJD6 (0.38) JMJD6KMT2AKEAP1KDM4EMKNK1
SCHEMBL25253170 0.79 JMJD6 (0.49) JMJD6KMT2AKEAP1KDM4EKDM5B
SCHEMBL31277599 0.79 JMJD6 (0.49) JMJD6KMT2AKEAP1KDM4EKDM5B
SCHEMBL30463448 0.76 KDM4E (0.44) JMJD6KMT2AKEAP1KDM4EMKNK1
SCHEMBL30695146 0.76 KMT2A (0.41) JMJD6KMT2AKEAP1KDM4EMKNK1
SCHEMBL18157906 0.71 KMT2A (0.64) JMJD6KMT2AKEAP1KDM4EMKNK1
SCHEMBL29153859 0.71 KMT2A (0.44) JMJD6KMT2AKEAP1MKNK1MKNK2
SCHEMBL208629 0.69
SCHEMBL17812984 0.67 KMT2A (0.54) JMJD6KMT2AKEAP1KDM5BSCN4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119790055-A Pyrazolopyrimidine compound and medical use thereof 日本烟草产业株式会社 2025-04-08 CN disclosed