Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.49 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | LOX | P28300 | 2/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.46 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14899838 | 0.81 | CFD (0.66) | CFDHTR2CPPARGMMP13LOXL2 | |
| SCHEMBL4928443 | 0.81 | CFD (0.74) | CFDHTR2CPPARGLOXL2NR1H4 | |
| SCHEMBL308230 | 0.81 | CFD (0.59) | CFDHTR2CPPARGMMP13LOXL2 | |
| SCHEMBL4925434 | 0.79 | CFD (0.62) | CFDHTR2CPPARGNR1H4HDAC2 | |
| SCHEMBL16079859 | 0.77 | CFD (0.57) | CFDHTR2CMMP13LOXL2NR1H4 | |
| SCHEMBL14081049 | 0.76 | LOXL2 (0.61) | CFDHTR2CMMP13LOXL2GAA | |
| SCHEMBL4927927 | 0.75 | HASPIN (0.58) | CFDHTR2CNR1H4HDAC2HDAC8 | |
| SCHEMBL27659355 | 0.75 | CFD (0.82) | CFDHTR2CPPARGLOXL2NR1H4 | |
| SCHEMBL529613 | 0.74 | FOLH1 (0.56) | — | |
| SCHEMBL17692442 | 0.74 | HDAC2 (0.59) | CFDPPARGMMP13NR1H4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2629889-B1 | RUTHENIUM COMPLEXES AND THEIR USES IN PROCESSES FOR FORMATION AND/OR HYDROGENATION OF ESTERS, AMIDES AND DERIVATIVES THEREOF | YEDA RES & DEV (IL) | 2019-04-03 | — | — | EP | disclosed |