Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | REN | P00797 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | PFKFB2 | O60825 | 3/20 | 0.43 |
| ▸ | PFKFB1 | P16118 | 3/20 | 0.43 |
| ▸ | PFKFB3 | Q16875 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CTSC | P53634 | 3/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22295691 | 1.00 | MEN1 (0.49) | MEN1KMT2ARENHDAC3HDAC1 | |
| SCHEMBL25398492 | 0.90 | TSHR (0.47) | PFKFB2PFKFB1PFKFB3CTSCTERT | |
| SCHEMBL24003652 | 0.90 | TSHR (0.47) | PFKFB2PFKFB1PFKFB3CTSCTERT | |
| SCHEMBL20863893 | 0.83 | PFKFB1 (0.49) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL22295666 | 0.83 | PFKFB1 (0.49) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL23754361 | 0.79 | SCN3A (0.53) | MEN1KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL23754360 | 0.79 | SCN3A (0.53) | MEN1KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL2872463 | 0.77 | DPP7 (0.44) | MEN1KMT2ARENL3MBTL1CTSC | |
| SCHEMBL2872459 | 0.77 | DPP7 (0.44) | MEN1KMT2ARENL3MBTL1CTSC | |
| SCHEMBL2870216 | 0.77 | DPP7 (0.44) | MEN1KMT2ARENL3MBTL1CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019065964-A1 | ANTIBODY-PYRROLOBENZODIAZEPINE DERIVATIVE CONJUGATE | 第一三共株式会社 | 2019-04-04 | — | — | WO | disclosed |