Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 13/20 | 0.60 |
| ▸ | ERCC5 | P28715 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20856770 | 0.90 | FEN1 (0.71) | FEN1ERCC5 | |
| SCHEMBL20864098 | 0.87 | FEN1 (0.53) | FEN1ERCC5LMNAMAPTALDH1A1 | |
| SCHEMBL20864158 | 0.85 | FEN1 (0.71) | FEN1ERCC5LMNAMAPTALDH1A1 | |
| SCHEMBL20856839 | 0.85 | FEN1 (0.72) | FEN1ERCC5LMNAGLAMAPT | |
| SCHEMBL5113032 | 0.84 | FEN1 (0.66) | FEN1ERCC5LMNAGLAMAPT | |
| SCHEMBL5104130 | 0.83 | FEN1 (0.59) | FEN1ERCC5LMNAGLAMAPT | |
| SCHEMBL20864172 | 0.83 | FEN1 (0.51) | FEN1ERCC5LMNAMAPTALDH1A1 | |
| SCHEMBL20864162 | 0.82 | FEN1 (0.63) | FEN1ERCC5LMNAMAPTALDH1A1 | |
| SCHEMBL20864188 | 0.81 | FEN1 (0.48) | FEN1ERCC5LMNAMAPTALDH1A1 | |
| SCHEMBL20856824 | 0.81 | ERCC5 (0.52) | FEN1ERCC5MAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11584755-B2 | Dihydrothieno[3,2-b]pyridine compounds | IDEAYA BIOSCIENCES, INC. (US) | 2023-02-21 | — | — | US | disclosed |
| WO-2019067442-A1 | DIHYDROTHIENO[3,2-b]PYRIDINE COMPOUNDS | IDEAYA BIOSCIENCES, INC. (US) | 2019-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11584755-B2 | Dihydrothieno[3,2-b]pyridine compounds | DHFR, CYC1, CYCS | FEN1 3399/4885ERCC5 3889/4885LMNA 2628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.