Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 19/20 | 0.74 |
| ▸ | FEN1 | P39748 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25053694 | 0.86 | FEN1 (0.81) | ERCC5FEN1 | |
| SCHEMBL20864419 | 0.85 | ERCC5 (1.00) | ERCC5FEN1 | |
| SCHEMBL20864115 | 0.85 | ERCC5 (1.00) | ERCC5FEN1 | |
| SCHEMBL20864439 | 0.83 | ERCC5 (1.00) | ERCC5FEN1 | |
| SCHEMBL29805009 | 0.83 | ERCC5 (1.00) | ERCC5FEN1 | |
| SCHEMBL20864251 | 0.83 | ERCC5 (1.00) | ERCC5FEN1 | |
| SCHEMBL20864120 | 0.83 | ERCC5 (1.00) | ERCC5FEN1 | |
| SCHEMBL20864269 | 0.82 | ERCC5 (0.72) | ERCC5FEN1 | |
| SCHEMBL20864255 | 0.82 | FEN1 (1.00) | ERCC5FEN1 | |
| SCHEMBL29805027 | 0.82 | FEN1 (1.00) | ERCC5FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11584755-B2 | Dihydrothieno[3,2-b]pyridine compounds | IDEAYA BIOSCIENCES, INC. (US) | 2023-02-21 | — | — | US | disclosed |
| US-11584755-B2 | Dihydrothieno[3,2-b]pyridine compounds | IDEAYA BIOSCIENCES, INC. (US) | 2023-02-21 | — | — | US | disclosed |
| US-20220227780-A1 | DIHYDROTHIENO[3,2-b]PYRIDINE COMPOUNDS | IDEAYA BIOSCIENCES, INC. | 2022-07-21 | — | — | US | disclosed |
| WO-2019067442-A1 | DIHYDROTHIENO[3,2-b]PYRIDINE COMPOUNDS | IDEAYA BIOSCIENCES, INC. (US) | 2019-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11584755-B2 | Dihydrothieno[3,2-b]pyridine compounds | DHFR, CYC1, CYCS | ERCC5 3889/4885FEN1 3399/4885 |
| US-20220227780-A1 | DIHYDROTHIENO[3,2-b]PYRIDINE COMPOUNDS | DHFR, CYC1, CYCS | ERCC5 3889/4885FEN1 3399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.