SCHEMBL20864772

SCHEMBL20864772

N[C@H](Cc1ccccc1)C(=O)N1CCC(O)(Cn2cnc3cc(Cl)ccc3c2=O)CC1

nearest known ligand 0.71

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
USP7 Q93009 16/20 0.71
USP19 O94966 4/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20864288 1.00 USP7 (0.71) USP7USP19
SCHEMBL20864304 0.90 USP7 (0.72) USP7USP19
SCHEMBL20864523 0.90 USP7 (0.71) USP7USP19
SCHEMBL20864290 0.90 USP7 (0.80) USP7USP19
SCHEMBL20864315 0.90 USP7 (0.80) USP7USP19
SCHEMBL14744229 0.90 USP7 (0.80) USP7USP19
SCHEMBL20864341 0.88 USP7 (0.69) USP7USP19
SCHEMBL20864524 0.88 USP7 (0.69) USP7USP19
SCHEMBL17937970 0.87 USP7 (0.85) USP7USP19
SCHEMBL20864496 0.87 USP7 (0.68) USP7USP19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265070-A1 NOVEL USP7 INHIBITORS FOR TREATING MULTIPLE MYELOMA DANA-FARBER CANCER INSTITUTE, INC. 2023-08-24 US disclosed
US-20230265070-A1 NOVEL USP7 INHIBITORS FOR TREATING MULTIPLE MYELOMA DANA-FARBER CANCER INSTITUTE, INC. 2023-08-24 US disclosed
US-20200347031-A1 NOVEL USP7 INHIBITORS FOR TREATING MULTIPLE MYELOMA DANA-FARBER CANCER INSTITUTE, INC. 2020-11-05 US disclosed
WO-2019067503-A1 NOVEL USP7 INHIBITORS FOR TREATING MULTIPLE MYELOMA DANA-FARBER CANCER INSTITUTE, INC. (US) 2019-04-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265070-A1 NOVEL USP7 INHIBITORS FOR TREATING MULTIPLE MYELOMA USP7, USP1, USP3 USP7 1/4885USP19 8/4885
US-20200347031-A1 NOVEL USP7 INHIBITORS FOR TREATING MULTIPLE MYELOMA USP7, USP1, USP3 USP7 1/4885USP19 8/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.