SCHEMBL20864882

SCHEMBL20864882

c1ccc(-c2nc3ccccc3c3c2cc(N(c2ccccc2)c2ccccc2)c2oc4ccccc4c23)cc1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.39
CSF1R P07333 1/20 0.39
PDGFRB P09619 1/20 0.39
MAPT P10636 1/20 0.39
KIT P10721 1/20 0.39
FLT3 P36888 1/20 0.39
KMT2A Q03164 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
NUDT1 P36639 2/20 0.35
ADORA2A P29274 1/20 0.35
PDE10A Q9Y233 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20864884 0.97 MEN1 (0.36) MEN1CSF1RPDGFRBMAPTKIT
SCHEMBL20864885 0.95 MEN1 (0.37) MEN1CSF1RPDGFRBMAPTKIT
SCHEMBL20864883 0.94 MEN1 (0.35) MEN1CSF1RPDGFRBMAPTKIT
SCHEMBL20864954 0.93 MEN1 (0.36) MEN1CSF1RPDGFRBMAPTKIT
SCHEMBL20864903 0.93 MAPT (0.34) MEN1CSF1RPDGFRBMAPTKIT
SCHEMBL20864643 0.93 MEN1 (0.34) MEN1CSF1RPDGFRBMAPTKIT
SCHEMBL20864892 0.91 MEN1 (0.34) MEN1CSF1RPDGFRBMAPTKIT
SCHEMBL20864904 0.90 MAPT (0.35) MEN1CSF1RPDGFRBMAPTKIT
SCHEMBL20864905 0.90 MAPT (0.33) MEN1CSF1RPDGFRBMAPTKIT
SCHEMBL20864891 0.87 MAPT (0.36) MEN1CSF1RPDGFRBMAPTKIT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190103560-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME SOULBRAIN CO., LTD. (KR) 2019-04-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190103560-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME CRY1, CRY2, CYP1A1 MEN1 495/4885CSF1R 368/4885PDGFRB 3980/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.