Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 3/20 | 0.60 |
| ▸ | EGFR | P00533 | 1/20 | 0.60 |
| ▸ | CDK4 | P11802 | 11/20 | 0.53 |
| ▸ | CCND1 | P24385 | 11/20 | 0.53 |
| ▸ | CCNE2 | O96020 | 8/20 | 0.53 |
| ▸ | CCNE1 | P24864 | 8/20 | 0.53 |
| ▸ | CDK2 | P24941 | 8/20 | 0.53 |
| ▸ | CAMK2B | Q13554 | 7/20 | 0.53 |
| ▸ | CAMK2G | Q13555 | 7/20 | 0.53 |
| ▸ | CAMK2D | Q13557 | 7/20 | 0.53 |
| ▸ | CAMK2A | Q9UQM7 | 7/20 | 0.53 |
| ▸ | CCNB2 | O95067 | 5/20 | 0.53 |
| ▸ | CDK1 | P06493 | 5/20 | 0.53 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.53 |
| ▸ | CCNB3 | Q8WWL7 | 5/20 | 0.53 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.53 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.53 |
| ▸ | PRKACA | P17612 | 2/20 | 0.53 |
| ▸ | PRKACG | P22612 | 2/20 | 0.53 |
| ▸ | PRKACB | P22694 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6696776 | 0.80 | DYRK1A (0.41) | PRKCAEGFRCDK5CDK5R1MAPT | |
| SCHEMBL29732438 | 0.77 | DYRK1A (0.47) | GSK3B | |
| SCHEMBL20115833 | 0.77 | DYRK1A (0.47) | GSK3B | |
| SCHEMBL29914033 | 0.76 | PRKCA (1.00) | PRKCAEGFRCDK4CCND1CCNE2 | |
| SCHEMBL22566996 | 0.76 | CDK4 (0.83) | PRKCAEGFRCDK4CCND1CCNE2 | |
| SCHEMBL8123086 | 0.76 | PRKCA (0.66) | PRKCAEGFRCDK4CCND1CCNE2 | |
| SCHEMBL20865106 | 0.76 | PRKCA (0.66) | PRKCAEGFRCDK4CCND1CCNE2 | |
| SCHEMBL29741367 | 0.76 | PRKCA (0.66) | PRKCAEGFRCDK4CCND1CCNE2 | |
| SCHEMBL6622398 | 0.76 | PRKCA (1.00) | PRKCAEGFRCDK4CCND1CCNE2 | |
| SCHEMBL20115856 | 0.71 | DYRK1A (0.49) | CDK5CDK5R1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11319320-B2 | PIM kinase inhibitor compositions, methods, and uses thereof | SNAP BIO, INC. (US) | 2022-05-03 | — | — | US | disclosed |
| US-20200331914-A1 | PIM KINASE INHIBITOR COMPOSITIONS, METHODS, AND USES THEREOF | SNAP BIO, INC. | 2020-10-22 | — | — | US | disclosed |
| WO-2019067396-A1 | ZAP-70 KINASE INHIBITOR COMPOSITIONS, METHODS AND USES THEREOF | SNAP BIO, INC. (US) | 2019-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200331914-A1 | PIM KINASE INHIBITOR COMPOSITIONS, METHODS, AND USES THEREOF | PIM1, PIM2, PIM3 | PRKCA 19/4885EGFR 366/4885CDK4 221/4885 |
| US-11319320-B2 | PIM kinase inhibitor compositions, methods, and uses thereof | PIM1, PIM2, PIM3 | PRKCA 19/4885EGFR 366/4885CDK4 221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.