SCHEMBL20865261

SCHEMBL20865261

CCOc1cc(C=N)ccc1O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.70
MEN1 O00255 8/20 0.68
KMT2A Q03164 8/20 0.68
TOP2A P11388 1/20 0.60
ABL1 P00519 1/20 0.59
ABCB1 P08183 1/20 0.59
BCR P11274 1/20 0.59
ALPI P09923 1/20 0.56
ALPG P10696 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
HPGD P15428 2/20 0.55
KDM4E B2RXH2 1/20 0.55
PIM1 P11309 2/20 0.52
PIM3 Q86V86 2/20 0.52
PIM2 Q9P1W9 2/20 0.52
GAA P10253 5/20 0.51
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
PTGS1 P23219 1/20 0.50
PTGS2 P35354 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethyl Vanillin SCHEMBL719058 0.82 ALDH1A1 (1.00) ALDH1A1MEN1KMT2ATOP2AABL1
Ethyl Vanillin SCHEMBL29351334 0.82 ALDH1A1 (1.00) ALDH1A1MEN1KMT2ATOP2AABL1
Ethyl Vanillin SCHEMBL30247 0.82 ALDH1A1 (1.00) ALDH1A1MEN1KMT2ATOP2AABL1
SCHEMBL8630168 0.82 ALDH1A1 (0.70) ALDH1A1MEN1KMT2ATOP2AABL1
SCHEMBL685779 0.82 ALDH1A1 (0.70) ALDH1A1MEN1KMT2ATOP2AABL1
SCHEMBL30122702 0.82 ALDH1A1 (0.70) ALDH1A1MEN1KMT2ATOP2AABL1
SCHEMBL6560457 0.81 ALDH1A1 (0.68) ALDH1A1MEN1KMT2ATOP2AABL1
SCHEMBL11606178 0.81 ALDH1A1 (0.68) ALDH1A1MEN1KMT2ATOP2AABL1
SCHEMBL18328760 0.81 ALDH1A1 (0.68) ALDH1A1MEN1KMT2ATOP2AABL1
SCHEMBL22493034 0.81 ALDH1A1 (0.68) ALDH1A1MEN1KMT2ATOP2AABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102417462-A Preparation method of 4-hydroxy-3-ethoxybenzylamine hydrochloride SHANGHAI HUAYI GROUP CO 2012-04-18 CN claimed
EP-3728532-B1 ODOROUS ACETALS OF ETHYL VANILLIN AND ETHYL VANILLIN DERIVATIVES S H KELKAR AND COMPANY LTD (IN) 2021-11-10 EP disclosed
WO-2019067511-A1 MATERIALS AND METHODS USEFUL TO INDUCE CANCER CELL DEATH VIA METHUOSIS OR AUTOPHAGY OR A COMBINATION THEREOF THE UNIVERSITY OF TOLEDO (US) 2019-04-04 WO disclosed
CN-102417462-A Preparation method of 4-hydroxy-3-ethoxybenzylamine hydrochloride SHANGHAI HUAYI GROUP CO 2012-04-18 CN disclosed