Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.54 |
| ▸ | ALPI | P09923 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | XIAP | P98170 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30037334 | 0.85 | SLC7A5 (0.61) | KMT2AALDH1A1MEN1MAPTSLC7A5 | |
| SCHEMBL3059437 | 0.85 | SLC7A5 (0.61) | KMT2AALDH1A1MEN1MAPTSLC7A5 | |
| SCHEMBL4943107 | 0.85 | SLC7A5 (0.61) | KMT2AALDH1A1MEN1MAPTSLC7A5 | |
| SCHEMBL20865324 | 0.85 | CA12 (0.48) | KMT2AALDH1A1MEN1MAPTRXFP1 | |
| SCHEMBL25388169 | 0.84 | ALDH1A1 (0.57) | KMT2AALDH1A1MEN1MAPTSLC7A5 | |
| SCHEMBL25386567 | 0.84 | SLC7A5 (0.56) | KMT2AALDH1A1MEN1MAPTSLC7A5 | |
| SCHEMBL25388174 | 0.84 | ALDH1A1 (0.57) | KMT2AALDH1A1MEN1MAPTSLC7A5 | |
| SCHEMBL25386565 | 0.84 | SLC7A5 (0.56) | KMT2AALDH1A1MEN1MAPTSLC7A5 | |
| SCHEMBL12838404 | 0.83 | SLC7A5 (0.54) | KMT2AALDH1A1MEN1MAPTSLC7A5 | |
| SCHEMBL1530915 | 0.83 | SLC7A5 (0.54) | KMT2AALDH1A1MEN1MAPTSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019067543-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-04-04 | — | — | WO | disclosed |