Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.54 |
| ▸ | ALPI | P09923 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | XIAP | P98170 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25388169 | 1.00 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL20865323 | 0.84 | KMT2A (0.57) | ALDH1A1SMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL25386567 | 0.84 | SLC7A5 (0.56) | ALDH1A1SMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL25386565 | 0.84 | SLC7A5 (0.56) | ALDH1A1SMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL1530915 | 0.83 | SLC7A5 (0.54) | ALDH1A1SMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL12838404 | 0.83 | SLC7A5 (0.54) | ALDH1A1SMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL1530907 | 0.83 | SLC7A5 (0.54) | ALDH1A1SMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL25388820 | 0.82 | NOS3 (0.64) | ALDH1A1SMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL25388823 | 0.82 | NOS3 (0.64) | ALDH1A1SMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL4943107 | 0.82 | SLC7A5 (0.61) | ALDH1A1SMN1; SMN2MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250197448-A1 | CYCLOPEPTIBODIES AND USES THEREOF | UNIVERSITY OF ROCHESTER (US) | 2025-06-19 | — | — | US | claimed |
| US-20250197448-A1 | CYCLOPEPTIBODIES AND USES THEREOF | UNIVERSITY OF ROCHESTER (US) | 2025-06-19 | — | — | US | disclosed |
| WO-2023173084-A9 | CYCLOPEPTIBODIES AND USES THEREOF | UNIVERSITY OF ROCHESTER (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2023173084-A1 | CYCLOPEPTIBODIES AND USES THEREOF | UNIVERSITY OF ROCHESTER (US) | 2023-09-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250197448-A1 | CYCLOPEPTIBODIES AND USES THEREOF | FCGR3B, FCGRT, FCGR2A | ALDH1A1 4523/4885SMN1; SMN2 4871/4885MEN1 4859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.