Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.36 |
| ▸ | GRM6 | O15303 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL482018 | 0.90 | MAPT (0.43) | LMNAALDH1A1MAPTTDP1GRIA1 | |
| SCHEMBL15365148 | 0.86 | ALDH1A1 (0.45) | LMNAALDH1A1MAPTKDM4ETDP1 | |
| SCHEMBL15365263 | 0.86 | ALDH1A1 (0.45) | LMNAALDH1A1MAPTKDM4ETDP1 | |
| SCHEMBL15366047 | 0.86 | ALDH1A1 (0.45) | LMNAALDH1A1MAPTKDM4ETDP1 | |
| SCHEMBL5651215 | 0.86 | MAPT (0.45) | LMNAALDH1A1MAPTKDM4ETDP1 | |
| SCHEMBL15365139 | 0.86 | MAPT (0.45) | LMNAALDH1A1MAPTKDM4ETDP1 | |
| SCHEMBL15365285 | 0.83 | MAPT (0.40) | LMNAALDH1A1MAPTKDM4ETDP1 | |
| SCHEMBL15365067 | 0.83 | MAPT (0.40) | LMNAALDH1A1MAPTKDM4ETDP1 | |
| SCHEMBL15365609 | 0.81 | ALDH1A1 (0.41) | LMNAALDH1A1MAPTKDM4ETDP1 | |
| SCHEMBL15372369 | 0.81 | LMNA (0.40) | LMNAALDH1A1MAPTKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10251886-B1 | 4-anilinoquinazoline derivative and albumin conjugates thereof | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2019-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10251886-B1 | 4-anilinoquinazoline derivative and albumin conjugates thereof | KRAS, NRAS, ALB | LMNA 3910/4885PDE4B 3785/4885ALDH1A1 1193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.