Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20866762 | 0.88 | PIK3CA (0.30) | — | |
| SCHEMBL20866963 | 0.85 | PIK3CD (0.30) | SMN1; SMN2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL18394458 | 0.83 | KDM4E (0.42) | MAPK1SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL20867257 | 0.82 | SYK (0.31) | — | |
| SCHEMBL24612188 | 0.81 | PIK3CD (0.30) | MAPK1SMN1; SMN2KDM4EALDH1A1GAA | |
| SCHEMBL20867295 | 0.79 | — | — | |
| SCHEMBL24612210 | 0.70 | FBP1 (0.31) | KDM4E | |
| SCHEMBL20866838 | 0.70 | ATM (0.32) | SMN1; SMN2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL24612293 | 0.69 | ATM (0.31) | SMN1; SMN2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL18394800 | 0.69 | KDM4E (0.43) | MAPK1KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019067864-A1 | COMBINATION PHARMACEUTICAL AGENTS AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2019-04-04 | — | — | WO | disclosed |