⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20867257 | 0.84 | SYK (0.31) | — | |
| SCHEMBL20866963 | 0.84 | PIK3CD (0.30) | — | |
| SCHEMBL20866762 | 0.81 | PIK3CA (0.30) | — | |
| SCHEMBL24612188 | 0.81 | PIK3CD (0.30) | — | |
| SCHEMBL20866691 | 0.79 | MAPK1 (0.31) | — | |
| SCHEMBL20866838 | 0.76 | ATM (0.32) | — | |
| SCHEMBL20867306 | 0.74 | ATM (0.31) | — | |
| SCHEMBL24612210 | 0.72 | FBP1 (0.31) | — | |
| SCHEMBL24612293 | 0.70 | ATM (0.31) | — | |
| SCHEMBL20866960 | 0.69 | ATM (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019067864-A1 | COMBINATION PHARMACEUTICAL AGENTS AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2019-04-04 | — | — | WO | disclosed |