Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 11/20 | 0.34 |
| ▸ | NOTCH1 | P46531 | 3/20 | 0.34 |
| ▸ | RBPJ | Q06330 | 3/20 | 0.34 |
| ▸ | CCKBR | P32239 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CCKAR | P32238 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20867288 | 0.87 | CBLB (0.46) | CBLBNOTCH1RBPJCCKBRCCKAR | |
| SCHEMBL20866780 | 0.87 | CBLB (0.46) | CBLBNOTCH1RBPJCCKBRCCKAR | |
| SCHEMBL20866656 | 0.83 | CCKBR (0.38) | CBLBCCKBRCCKAR | |
| SCHEMBL20867202 | 0.78 | CBLB (0.46) | CBLBNOTCH1RBPJCCKBRCCKAR | |
| SCHEMBL24612224 | 0.78 | CBLB (0.44) | CBLBNOTCH1RBPJCCKBRCCKAR | |
| SCHEMBL20866688 | 0.76 | NOTCH1 (0.43) | CBLBNOTCH1RBPJCCKBRCCKAR | |
| SCHEMBL20866674 | 0.76 | CBLB (0.59) | CBLBCCKBRCCKAR | |
| SCHEMBL24611909 | 0.76 | CBLB (0.59) | CBLBCCKBRCCKAR | |
| SCHEMBL20866783 | 0.73 | NOTCH1 (0.42) | CBLBNOTCH1RBPJCCKBRCCKAR | |
| SCHEMBL20866782 | 0.73 | NOTCH1 (0.42) | CBLBNOTCH1RBPJCCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019067864-A1 | COMBINATION PHARMACEUTICAL AGENTS AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2019-04-04 | — | — | WO | disclosed |