⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9482394 | 0.68 | — | — | |
| SCHEMBL10862607 | 0.65 | — | — | |
| SCHEMBL2421740 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL10377375 | 0.64 | NPC1 (0.47) | — | |
| SCHEMBL6508131 | 0.63 | SMN1; SMN2 (0.61) | — | |
| SCHEMBL8011137 | 0.63 | L3MBTL1 (0.33) | — | |
| SCHEMBL3871228 | 0.63 | MAPT (0.54) | — | |
| Hydrochloric Acid SCHEMBL6512719 | 0.62 | SMN1; SMN2 (0.59) | — | |
| SCHEMBL20578862 | 0.62 | NPC1 (0.51) | — | |
| SCHEMBL20578808 | 0.62 | MAPT (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2050750-A2 | Multicyclic compounds and their use as inhibitors of PARP, VEGFR2 and MLK3 enzymes | CEPHALON, INC. (US) | 2009-04-22 | — | — | EP | claimed |
| US-7122679-B2 | Multicyclic compounds and the use thereof | CEPHALON, INC. (US) | 2006-10-17 | — | — | US | claimed |
| EP-0883616-B1 | DIHYDROBENZOFURAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | UNIV VANDERBILT (US) | 2004-08-25 | — | — | EP | claimed |
| US-6596706-B1 | For the treatment of circulatory diseases cerebral diseases | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-07-22 | — | — | US | claimed |
| EP-1029872-A1 | PIPERAZINE-CYCLODEXTRIN COMPLEXES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-08-23 | — | — | EP | claimed |
| US-5981547-A | FOR TREATING INFLAMMATION OR PAIN | THE PROCTER & GAMBLE COMPANY (US) | 1999-11-09 | — | — | US | claimed |
| US-5972957-A | ANALGESICS AND ANTIARTHRITIC AGENT | THE PROCTER & GAMBLE COMPANY (US) | 1999-10-26 | — | — | US | claimed |
| EP-0883616-A1 | DIHYDROBENZOFURAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1998-12-16 | — | — | EP | claimed |
| US-5821250-A | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents | THE PROCTER & GAMBLE COMPANY (US) | 1998-10-13 | — | — | US | claimed |
| EP-0624584-B1 | Piperazine derivatives useful as calmodulin inhibitors | DAIICHI SEIYAKU CO (JP) | 1998-08-19 | — | — | EP | claimed |
| EP-0087274-A2 | Pyrimidone derivatives | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1983-08-31 | — | — | EP | claimed |
| US-4388317-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1983-06-14 | — | — | US | claimed |
| US-4386211-A | Anti-ulcer urea compounds | G. D. SEARLE & CO. (US) | 1983-05-31 | — | — | US | claimed |
| EP-0074229-A1 | Triazole gastric anti-secretory agents | PFIZER INC. (US) | 1983-03-16 | — | — | EP | claimed |
| EP-0065825-A1 | Pyridine derivatives as histamine H2 antagonists | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1982-12-01 | — | — | EP | claimed |
| US-4352933-A | Chemical methods and intermediates for preparing substituted pyrimidinones | SMITHKLINE BECKMAN CORPORATION (US) | 1982-10-05 | — | — | US | claimed |
| EP-0058055-A2 | Process for preparing substituted pyrimidinones and intermediates therefor | SMITHKLINE BECKMAN CORPORATION (US) | 1982-08-18 | — | — | EP | claimed |
| US-4309435-A | HISTAMINE ANTAGONISTS | IMPERIAL CHEMICAL INDUSTRIES LTD. (GB) | 1982-01-05 | — | — | US | claimed |
| EP-0039989-A1 | Pyrimidone derivatives, processes for their preparation and pharmaceutical compositions containing them | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1981-11-18 | — | — | EP | claimed |
| EP-0010418-A1 | Antisecretory guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-04-30 | — | — | EP | claimed |