Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 17/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | VEGFA | P15692 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1604661 | 0.88 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL18243673 | 0.88 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL16726995 | 0.88 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL16727017 | 0.81 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL27701725 | 0.80 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL16729554 | 0.80 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL20868371 | 0.80 | EPAS1 (0.36) | EPAS1VEGFA | |
| SCHEMBL16726992 | 0.80 | TACR1 (0.36) | — | |
| SCHEMBL29028756 | 0.78 | EPAS1 (0.40) | EPAS1ALDH1A1VEGFAPSEN1PSEN2 | |
| SCHEMBL16729517 | 0.75 | KIF11 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111212830-B | N- (substituted sulfonyl) benzamide derivative and preparation method and medical application thereof | 浙江海正药业股份有限公司 | 2023-07-04 | — | — | CN | disclosed |
| WO-2019062848-A1 | N-(SUBSTITUTED SULFONYL)BENZAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | 浙江海正药业股份有限公司 | 2019-04-04 | — | — | WO | disclosed |