Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | APEX1 | P27695 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9587077 | 0.92 | NR1I2 (0.51) | PTGS1ABCB11PDE4DMAPTNR1I2 | |
| SCHEMBL9587073 | 0.92 | NR1I2 (0.51) | PTGS1ABCB11PDE4DMAPTNR1I2 | |
| SCHEMBL9781586 | 0.88 | MAPT (0.50) | PTGS1ABCB11PDE4DMAPTNR1I2 | |
| SCHEMBL9781582 | 0.88 | MAPT (0.50) | PTGS1ABCB11PDE4DMAPTNR1I2 | |
| SCHEMBL9016665 | 0.86 | KCNH2 (0.53) | PTGS1ABCB11PDE4DMAPTNR1I2 | |
| SCHEMBL9016668 | 0.86 | KCNH2 (0.53) | PTGS1ABCB11PDE4DMAPTNR1I2 | |
| SCHEMBL20886830 | 0.86 | MAPT (0.48) | PTGS1ABCB11PDE4DMAPTNR1I2 | |
| SCHEMBL20869566 | 0.86 | MAPT (0.48) | PTGS1ABCB11PDE4DMAPTNR1I2 | |
| SCHEMBL8180829 | 0.84 | MAPT (0.47) | PTGS1ABCB11PDE4DMAPTNR1I2 | |
| Iodide SCHEMBL9781606 | 0.83 | NR1I2 (0.46) | PTGS1ABCB11PDE4DMAPTNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190100534-A1 | Cephem Compounds with Latent Reactive Groups | GLADIUS PHARMACEUTICALS INC (CA) | 2019-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190100534-A1 | Cephem Compounds with Latent Reactive Groups | PGLS, GNE, COMT | PTGS1 1368/4885ABCB11 2792/4885PDE4D 2462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.