Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | EDNRA | P25101 | 4/20 | 0.36 |
| ▸ | EDNRB | P24530 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 4/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8404486 | 0.79 | SMN1; SMN2 (0.53) | BRD4SMN1; SMN2ALDH1A1KCNA3BRD2 | |
| SCHEMBL26124890 | 0.76 | ENPP3 (0.33) | SMN1; SMN2ALDH1A1CYP17A1CYP1A2LOXL2 | |
| SCHEMBL30917304 | 0.76 | ENPP3 (0.33) | SMN1; SMN2ALDH1A1CYP17A1CYP1A2LOXL2 | |
| SCHEMBL14837965 | 0.76 | IDO1 (0.38) | SMN1; SMN2ALDH1A1CYP3A4HSD17B10LOXL2 | |
| SCHEMBL25045603 | 0.76 | SMN1; SMN2 (0.36) | BRD4EDNRAEDNRBSMN1; SMN2ALDH1A1 | |
| SCHEMBL4119067 | 0.76 | EDNRA (0.42) | EDNRASMN1; SMN2KCNA3CYP1A2ALOX15 | |
| SCHEMBL20870713 | 0.76 | LMNA (0.47) | BRD4EDNRAEDNRBALDH1A1P2RX7 | |
| SCHEMBL13576849 | 0.76 | GRM4 (0.42) | EDNRAEDNRBSMN1; SMN2ALDH1A1KCNA3 | |
| SCHEMBL17185689 | 0.75 | PDE7A (0.33) | SMN1; SMN2ALDH1A1CYP17A1CYP1A2USP2 | |
| SCHEMBL20870711 | 0.73 | SMN1; SMN2 (0.41) | SMN1; SMN2LOXL2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019062802-A1 | ISOXAZOLINE DERIVATIVES AND THEIR USES IN AGRICULTURE RELATED APPLICATION | DONGGUAN HEC TECH R & D CO., LTD. (CN) | 2019-04-04 | — | — | WO | disclosed |