SCHEMBL20870905

SCHEMBL20870905

CC(c1noc2ccc(F)cc12)S(=O)(=O)C1=NOC(C)(C)C1

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HTR3A P46098 2/20 0.32
HTR2A P28223 2/20 0.32
DRD3 P35462 1/20 0.32
HTR7 P34969 1/20 0.31
PTGS1 P23219 1/20 0.30
PTGS2 P35354 1/20 0.30
SCD O00767 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20855338 1.00 HTR3A (0.32) HTR3AHTR2ADRD3HTR7PTGS1
SCHEMBL20855337 1.00 HTR3A (0.32) HTR3AHTR2ADRD3HTR7PTGS1
SCHEMBL20861670 0.91 PTGS1 (0.35) HTR2ADRD3HTR7PTGS1PTGS2
SCHEMBL20870596 0.91 PTGS1 (0.35) HTR2ADRD3HTR7PTGS1PTGS2
SCHEMBL20871127 0.91 PTGS1 (0.35) HTR2ADRD3HTR7PTGS1PTGS2
SCHEMBL20870891 0.85 ALDH1A1 (0.33)
SCHEMBL28912014 0.84 F2 (0.32)
SCHEMBL28555817 0.84 CA12 (0.35)
SCHEMBL20871001 0.83 HTR2A (0.31) HTR2ADRD3
SCHEMBL20870909 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109574945-B Isoxazoline derivatives and their use in agriculture 东莞市东阳光农药研发有限公司 2021-04-20 CN disclosed
WO-2019062802-A1 ISOXAZOLINE DERIVATIVES AND THEIR USES IN AGRICULTURE RELATED APPLICATION DONGGUAN HEC TECH R & D CO., LTD. (CN) 2019-04-04 WO disclosed