SCHEMBL20873159

SCHEMBL20873159

O=C(c1ccccc1I)c1cccc(I)c1I

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
PTPN2 P17706 2/20 0.40
PTPN1 P18031 2/20 0.40
PTPRF P10586 1/20 0.40
ALDH1A1 P00352 2/20 0.38
TP53 P04637 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
TSHR P16473 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PARP1 P09874 1/20 0.37
CDC25B P30305 1/20 0.37
ALOX15 P16050 1/20 0.37
GPR84 Q9NQS5 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
RXFP1 Q9HBX9 1/20 0.35
CNR1 P21554 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1298701 0.89 MEN1 (0.54) KMT2AMEN1TDP1PTPN2PTPN1
SCHEMBL3839465 0.86 KMT2A (0.52) KMT2AMEN1TDP1PTPN2PTPN1
SCHEMBL1298703 0.83 AKR1C3 (0.55) KMT2AMEN1TDP1ALDH1A1GAA
SCHEMBL31185117 0.78 ALDH1A1 (0.61) KMT2AMEN1TDP1ALDH1A1SMN1; SMN2
SCHEMBL3845299 0.78 AKR1C3 (0.54) KMT2AMEN1TDP1ALDH1A1GAA
SCHEMBL608549 0.77 ALDH1A1 (0.52) KMT2AMEN1TDP1ALDH1A1GAA
SCHEMBL19834640 0.77 ALDH1A1 (0.46) KMT2AMEN1TDP1ALDH1A1TP53
Thiophene SCHEMBL17785556 0.77 MEN1 (0.44) KMT2AMEN1TDP1PTPN2PTPN1
SCHEMBL4706826 0.77 CES2 (0.56) KMT2AMEN1TDP1ALDH1A1GAA
SCHEMBL8489362 0.77 PRNP (0.44) KMT2AMEN1TDP1PTPN2PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210380806-A1 POLYARYLENE SULFIDE RESIN COMPOSITION SK DISCOVERY CO., LTD. (KR) 2021-12-09 US disclosed
EP-3467029-B1 POLYARYLENE SULFIDE RESIN COMPOSITION HAVING EXCELLENT DUCTILITY AND DIMENSIONAL STABILITY SK CHEMICALS CO LTD (KR) 2021-06-09 EP disclosed
CN-112867763-A Polyarylene sulfide resin composition SK化学株式会社 2021-05-28 CN disclosed
US-20190177485-A1 POLYARYLENE SULFIDE RESIN COMPOSITION HAVING EXCELLENT DUCTILITY AND DIMENSIONAL STABILITY INITZ CO., LTD. (KR) 2019-06-13 US disclosed
EP-3467029-A1 POLYARYLENE SULFIDE RESIN COMPOSITION HAVING EXCELLENT DUCTILITY AND DIMENSIONAL STABILITY Initz Co., Ltd. (KR) 2019-04-10 EP disclosed