Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.39 |
| ▸ | TUBB | P07437 | 2/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11415941 | 0.81 | EGFR (0.50) | EGFRHDAC3TDP1HDAC1HDAC2 | |
| SCHEMBL1221307 | 0.80 | EGFR (0.44) | EGFRHDAC3TDP1HDAC1HDAC2 | |
| SCHEMBL29180935 | 0.80 | EGFR (0.44) | EGFRHDAC3TDP1HDAC1HDAC2 | |
| SCHEMBL2350390 | 0.80 | LCK (0.50) | — | |
| SCHEMBL1702508 | 0.80 | LCK (0.50) | — | |
| SCHEMBL1220655 | 0.79 | LMNA (0.43) | EGFRHDAC3TDP1HDAC1HDAC2 | |
| SCHEMBL579053 | 0.78 | EGFR (0.49) | EGFRHDAC3TDP1HDAC1HDAC2 | |
| SCHEMBL5858046 | 0.77 | EGFR (0.51) | EGFRHDAC3TDP1HDAC1HDAC2 | |
| SCHEMBL8722881 | 0.77 | EGFR (0.51) | EGFRHDAC3TDP1HDAC1HDAC2 | |
| SCHEMBL5858044 | 0.77 | EGFR (0.51) | EGFRHDAC3TDP1HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3056534-B1 | EXPANDABLE VINYL AROMATIC POLYMERIC COMPOSITIONS | VERSALIS SPA (IT) | 2019-04-10 | — | — | EP | claimed |