SCHEMBL20873757

SCHEMBL20873757

C#CCCCC(=O)NCCN

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.45
CYP2D6 P10635 2/20 0.45
CYP3A4 P08684 1/20 0.45
MAPT P10636 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
HSD17B10 Q99714 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
SLC6A5 Q9Y345 2/20 0.37
EPHX2 P34913 1/20 0.37
TSHR P16473 1/20 0.36
SELP P16109 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
FAAH O00519 2/20 0.34
CASP2 P42575 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16492569 0.88 L3MBTL1 (0.34) CYP1A2CYP2D6CYP3A4MAPTCYP2C9
SCHEMBL13193058 0.82 SELP (0.50) CYP1A2CYP2D6CYP3A4MAPTCYP2C9
SCHEMBL12598467 0.82 SLC6A5 (0.54) CYP1A2CYP2D6MAPTCYP2C9CYP2C19
SCHEMBL14198853 0.81 SLC6A5 (0.49) SLC6A5TSHRCA1CA2FAAH
SCHEMBL10124145 0.81 L3MBTL1 (0.49) CYP1A2CYP2D6CYP3A4MAPTCYP2C9
SCHEMBL11887064 0.81 HDAC3 (0.46) CYP1A2CYP2D6CYP3A4MAPTCYP2C9
SCHEMBL1223716 0.81 SLC6A5 (0.37) SLC6A5EPHX2TSHRSELPCA1
SCHEMBL16492547 0.81 SLC6A5 (0.41) CYP1A2CYP2D6MAPTCYP2C9CYP2C19
SCHEMBL25021999 0.80 CYP1A2 (0.41) CYP1A2CYP2D6CYP3A4MAPTCYP2C9
SCHEMBL19835757 0.79 CYP1A2 (0.44) CYP1A2CYP2D6CYP3A4MAPTCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11180696-B2 Fabrication of luminescent quantum dot thiol-yne nanocomposites with tailorable optical, thermal and mechanical properties THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2021-11-23 US claimed
EP-3694953-A1 FABRICATION OF LUMINESCENT QUANTUM DOT THIOL-YNE NANOCOMPOSITES WITH TAILORABLE OPTICAL, THERMAL, AND MECHANICAL PROPERTIES The Government of the United States of America as represented by the Secretary of the Navy (US) 2020-08-19 EP claimed
WO-2019074803-A1 FABRICATION OF LUMINESCENT QUANTUM DOT THIOL-YNE NANOCOMPOSITES WITH TAILORABLE OPTICAL, THERMAL, AND MECHANICAL PROPERTIES THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2019-04-18 WO claimed
US-20190106624-A1 Fabrication of Luminescent Quantum Dot Thiol-yne Nanocomposites With Tailorable Optical, Thermal and Mechanical Properties THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2019-04-11 US claimed
US-20250207029-A1 Luminescent Quantum Dot Thiol-yne Nanocomposites With Tailorable Optical, Thermal and Mechanical Properties THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2025-06-26 US disclosed
US-12247152-B2 Fabrication of luminescent quantum dot thiol-yne nanocomposites with tailorable optical, thermal and mechanical properties THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2025-03-11 US disclosed
US-12116519-B2 Fabrication of luminescent quantum dot thiol-yne nanocomposites with tailorable optical, thermal and mechanical properties THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2024-10-15 US disclosed
US-20220228061-A1 Fabrication of Luminescent Quantum Dot Thiol-yne Nanocomposites With Tailorable Optical, Thermal and Mechanical Properties THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2022-07-21 US disclosed
US-11180696-B2 Fabrication of luminescent quantum dot thiol-yne nanocomposites with tailorable optical, thermal and mechanical properties THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2021-11-23 US disclosed
US-20210324269-A1 Fabrication of Luminescent Quantum Dot Thiol-yne Nanocomposites With Tailorable Optical, Thermal and Mechanical Properties THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2021-10-21 US disclosed
EP-3694953-A1 FABRICATION OF LUMINESCENT QUANTUM DOT THIOL-YNE NANOCOMPOSITES WITH TAILORABLE OPTICAL, THERMAL, AND MECHANICAL PROPERTIES The Government of the United States of America as represented by the Secretary of the Navy (US) 2020-08-19 EP disclosed
WO-2019074803-A1 FABRICATION OF LUMINESCENT QUANTUM DOT THIOL-YNE NANOCOMPOSITES WITH TAILORABLE OPTICAL, THERMAL, AND MECHANICAL PROPERTIES THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2019-04-18 WO disclosed
US-20190106624-A1 Fabrication of Luminescent Quantum Dot Thiol-yne Nanocomposites With Tailorable Optical, Thermal and Mechanical Properties THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2019-04-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11180696-B2 Fabrication of luminescent quantum dot thiol-yne nanocomposites with tailorable optical, thermal and mechanical properties TYR, ALG3, YES1 CYP1A2 2073/4885CYP2D6 2554/4885CYP3A4 1615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.