Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 4/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17419208 | 1.00 | IRAK4 (0.37) | IRAK4LPLLIPGLMNAKDM4E | |
| SCHEMBL17420900 | 0.86 | IDO1 (0.38) | IRAK4LPLLIPGIDO1TDO2 | |
| SCHEMBL6584423 | 0.80 | MAPT (0.44) | IRAK4LPLLIPGLMNAKDM4E | |
| SCHEMBL17419195 | 0.76 | IRAK4 (0.39) | IRAK4LPLLIPGKDM4EIDO1 | |
| SCHEMBL593916 | 0.74 | LPL (0.50) | IRAK4LPLLIPGLMNAKDM4E | |
| SCHEMBL29241869 | 0.73 | IRAK4 (0.39) | IRAK4LPLLIPGSMN1; SMN2IDO1 | |
| SCHEMBL29037572 | 0.73 | MAPT (0.45) | IRAK4LPLLIPGKDM4EIDO1 | |
| SCHEMBL13313016 | 0.73 | KMT2A (0.50) | LMNAKDM4ETDP1SMN1; SMN2CYP2D6 | |
| SCHEMBL5141046 | 0.72 | LIPG (0.40) | IRAK4LPLLIPGLMNAKDM4E | |
| SCHEMBL23638462 | 0.70 | IRAK4 (0.43) | IRAK4LPLLIPGIDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190106426-A1 | IMIDAZOPYRAZINES AS LSD1 INHIBITORS | INCYTE CORPORATION | 2019-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190106426-A1 | IMIDAZOPYRAZINES AS LSD1 INHIBITORS | KDM1B, KDM2A, KDM1A | IRAK4 1197/4885LPL 4054/4885LIPG 3687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.