Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 2/20 | 0.67 |
| ▸ | TYMP | P19971 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ALB | P02768 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | PYGM | P11217 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL62321 | 1.00 | TK2 (0.67) | TK2TYMPALDH1A1LMNAALB | |
| SCHEMBL7182936 | 1.00 | TK2 (0.67) | TK2TYMPALDH1A1LMNAALB | |
| SCHEMBL1021637 | 1.00 | TK2 (0.67) | TK2TYMPALDH1A1LMNAALB | |
| SCHEMBL22992480 | 1.00 | TK2 (0.67) | TK2TYMPALDH1A1LMNAALB | |
| SCHEMBL62322 | 1.00 | TK2 (0.67) | TK2TYMPALDH1A1LMNAALB | |
| SCHEMBL22992424 | 1.00 | TK2 (0.67) | TK2TYMPALDH1A1LMNAALB | |
| SCHEMBL29509957 | 0.99 | TK2 (0.66) | TK2TYMPALDH1A1LMNAALB | |
| SCHEMBL14429106 | 0.95 | TK2 (0.62) | TK2TYMPALDH1A1LMNAALB | |
| SCHEMBL15691446 | 0.91 | TK2 (0.58) | TK2TYMPALDH1A1LMNAALB | |
| SCHEMBL15691496 | 0.91 | TK2 (0.58) | TK2TYMPALDH1A1LMNAALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117615752-A | RNA compositions comprising buffer substances and methods of making, storing, and using the same | 生物技术欧洲股份公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-117157400-A | Efficacy assays for therapeutic potential of encoding nucleic acids | 生物技术公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-116669709-A | Pharmaceutical composition comprising particles and mRNA and methods for preparing and storing the same | 生物技术公司 | 2023-08-29 | — | — | CN | disclosed |
| US-20230159922-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | US | disclosed |
| US-20230159922-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | US | disclosed |
| US-20230159922-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | US | disclosed |
| EP-4013428-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | Ionis Pharmaceuticals, Inc. (US) | 2022-06-22 | — | — | EP | disclosed |
| US-20210180137-A1 | Methods of Detecting Inherited Myopathies in Horses | UNM RAINFOREST INNOVATIONS | 2021-06-17 | — | — | US | disclosed |
| WO-2021030763-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2021-02-18 | — | — | WO | disclosed |
| WO-2021030763-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2021-02-18 | — | — | WO | disclosed |
| WO-2020072991-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2020-04-09 | — | — | WO | disclosed |
| US-20190106698-A1 | METHOD FOR APTAMER PAIR SELECTION | PROXIMITY BIOSCIENCES, LLC (US) | 2019-04-11 | — | — | US | disclosed |
| CN-105530952-A | Compositions and vaccines for treating lung cancer | CUREVAC GMBH | 2016-04-27 | — | — | CN | disclosed |
| CN-105517566-A | Compositions and vaccines for treating prostate cancer | CUREVAC GMBH | 2016-04-20 | — | — | CN | disclosed |
| CN-104840953-A | Compositions for treating prostate cancer (PCa) | CUREVAC GMBH | 2015-08-19 | — | — | CN | disclosed |
| CN-104812898-A | Methods of treating a metabolic syndrome by modulating heat shock protein (hsp) 90-beta | BERG PHARMA LLC | 2015-07-29 | — | — | CN | disclosed |
| CN-104619335-A | Compositions comprising an anti-PDGF aptamer and a VEGF antagonist | OPHTHOTECH CORP | 2015-05-13 | — | — | CN | disclosed |
| CN-103333890-B | RNA interference preparation used for treating viral hepatitis B | XIAMEN CHENGKUN BIOTECHNOLOGY CO LTD | 2015-04-15 | — | — | CN | disclosed |
| CN-103917664-A | Nuclease substrates | SPEEDX PTY LTD | 2014-07-09 | — | — | CN | disclosed |