SCHEMBL62322

SCHEMBL62322

COC1C(O)[C@H](CO)O[C@@H]1n1cc(C)c(=O)[nH]c1=O

nearest known ligand 0.67

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TK2 O00142 2/20 0.67
TYMP P19971 4/20 0.55
ALDH1A1 P00352 1/20 0.54
LMNA P02545 1/20 0.54
ALB P02768 1/20 0.54
POLB P06746 1/20 0.54
ADRA1A P35348 1/20 0.54
BLM P54132 1/20 0.54
PYGM P11217 3/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL62321 1.00 TK2 (0.67) TK2TYMPALDH1A1LMNAALB
SCHEMBL7182936 1.00 TK2 (0.67) TK2TYMPALDH1A1LMNAALB
SCHEMBL20875706 1.00 TK2 (0.67) TK2TYMPALDH1A1LMNAALB
SCHEMBL1021637 1.00 TK2 (0.67) TK2TYMPALDH1A1LMNAALB
SCHEMBL22992480 1.00 TK2 (0.67) TK2TYMPALDH1A1LMNAALB
SCHEMBL22992424 1.00 TK2 (0.67) TK2TYMPALDH1A1LMNAALB
SCHEMBL29509957 0.99 TK2 (0.66) TK2TYMPALDH1A1LMNAALB
SCHEMBL14429106 0.95 TK2 (0.62) TK2TYMPALDH1A1LMNAALB
SCHEMBL15691446 0.91 TK2 (0.58) TK2TYMPALDH1A1LMNAALB
SCHEMBL15691496 0.91 TK2 (0.58) TK2TYMPALDH1A1LMNAALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1315 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12509698-B2 Synthesis and structure of high potency RNA therapeutics ARCTURUS THERAPEUTICS, INC. (US) 2025-12-30 US claimed
US-20250270299-A1 METHODS OF USING COMPOSITIONS COMPRISING SBI DOMAINS HELIX NANOTECHNOLOGIES INC 2025-08-28 US claimed
EP-3630985-B1 SYNTHESIS AND STRUCTURE OF HIGH POTENCY RNA THERAPEUTICS ARCTURUS THERAPEUTICS INC (US) 2025-08-27 EP claimed
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES, INC. (US) 2025-08-21 US claimed
EP-4601656-A1 MODIFIED OLIGONUCLEOTIDES Pharmorage Pty Limited (AU) 2025-08-20 EP claimed
WO-2025122628-A1 CIRCULARIZED RNAS AND METHODS OF MAKING THE SAME HELIX NANOTECHNOLOGIES INC (US) 2025-06-12 WO claimed
WO-2025081087-A1 METHODS FOR CENTRAL NERVOUS SYSTEM NUCLEIC ACID DELIVERY ARCTURUS THERAPEUTICS, INC. (US) 2025-04-17 WO claimed
WO-2025081080-A1 COMPOSITIONS FOR CENTRAL NERVOUS SYSTEM NUCLEIC ACID DELIVERY ARCTURUS THERAPEUTICS, INC. (US) 2025-04-17 WO claimed
US-20250049950-A1 NUCLEIC ACIDS AND METHODS OF TREATMENT FOR CYSTIC FIBROSIS ARCTURUS THERAPEUTICS, INC. 2025-02-13 US claimed
WO-2025024442-A1 COMPOSITIONS AND METHODS FOR TREATING CONDITIONS ASSOCIATED WITH BSEP DEFICIENCY ULTRAGENYX PHARMACEUTICAL INC. (US) 2025-01-30 WO claimed
WO-2008109500-A2 NUCLEIC ACID COMPOUNDS FOR INHIBITING PRKCA GENE EXPRESSION AND USES THEREOF MDRNA, INC. (US) 2008-09-12 WO claimed
EP-1948822-A1 MULTICOMPONENT NUCLEIC ACID ENZYMES AND METHODS FOR THEIR USE JOHNSON & JOHNSON RESEARCH PTY LIMITED (AU) 2008-07-30 EP claimed
US-20070259832-A1 Nucleotide mimics and their prodrugs BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2007-11-08 US claimed
US-20070231810-A1 Multicomponent nucleic acid enzymes and methods for their use SPEEDX PTY LTD (AU) 2007-10-04 US claimed
WO-2007041774-A1 MULTICOMPONENT NUCLEIC ACID ENZYMES AND METHODS FOR THEIR USE JOHNSON & JOHNSON RESEARCH PTY LIMITED (AU) 2007-04-19 WO claimed
US-20040059104-A1 Nucleotide mimics and their prodrugs BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2004-03-25 US claimed
US-6706691-B1 BIOAVAILABILITY OF COMPOSITIONS METABOLIZED BY THE GUT P450 ISOZYMES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2004-03-16 US claimed
US-20030007961-A1 Orthomolecular vitamin E derivatives WILBURN MICHAEL D (US) 2003-01-09 US claimed
EP-0795029-A1 CHEMICAL LABELLING OF OBJECTS Pabio (NO) 1997-09-17 EP claimed
WO-1996017954-A1 CHEMICAL LABELLING OF OBJECTS PABIO (DK) 1996-06-13 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070259832-A1 Nucleotide mimics and their prodrugs NUDT14, ENTPD5, MTAP TK2 207/4885TYMP 7/4885ALDH1A1 2112/4885
US-20250049950-A1 NUCLEIC ACIDS AND METHODS OF TREATMENT FOR CYSTIC FIBROSIS CFTR, RNMT, RNGTT TK2 1720/4885TYMP 2570/4885ALDH1A1 4062/4885
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA RNASE1, POLRMT, TERT TK2 124/4885TYMP 921/4885ALDH1A1 2668/4885
US-12509698-B2 Synthesis and structure of high potency RNA therapeutics IGF2BP3, SERPINC1, IGF2BP2 TK2 1650/4885TYMP 2704/4885ALDH1A1 4110/4885
US-20030007961-A1 Orthomolecular vitamin E derivatives RBP4, RBP1, VDR TK2 3708/4885TYMP 4834/4885ALDH1A1 1020/4885
US-20040059104-A1 Nucleotide mimics and their prodrugs NUDT14, ENTPD5, MTAP TK2 207/4885TYMP 7/4885ALDH1A1 2112/4885
US-20250270299-A1 METHODS OF USING COMPOSITIONS COMPRISING SBI DOMAINS C1QBP, SSB, SARNP TK2 3025/4885TYMP 36/4885ALDH1A1 4618/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.