SCHEMBL7182936

SCHEMBL7182936

COC1[C@H](n2cc(C)c(=O)[nH]c2=O)O[C@H](CO)[C@H]1O

nearest known ligand 0.67

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TK2 O00142 2/20 0.67
TYMP P19971 4/20 0.55
ALDH1A1 P00352 1/20 0.54
LMNA P02545 1/20 0.54
ALB P02768 1/20 0.54
POLB P06746 1/20 0.54
ADRA1A P35348 1/20 0.54
BLM P54132 1/20 0.54
PYGM P11217 3/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL62321 1.00 TK2 (0.67) TK2TYMPALDH1A1LMNAALB
SCHEMBL20875706 1.00 TK2 (0.67) TK2TYMPALDH1A1LMNAALB
SCHEMBL1021637 1.00 TK2 (0.67) TK2TYMPALDH1A1LMNAALB
SCHEMBL22992480 1.00 TK2 (0.67) TK2TYMPALDH1A1LMNAALB
SCHEMBL62322 1.00 TK2 (0.67) TK2TYMPALDH1A1LMNAALB
SCHEMBL22992424 1.00 TK2 (0.67) TK2TYMPALDH1A1LMNAALB
SCHEMBL29509957 0.99 TK2 (0.66) TK2TYMPALDH1A1LMNAALB
SCHEMBL14429106 0.95 TK2 (0.62) TK2TYMPALDH1A1LMNAALB
SCHEMBL15691446 0.91 TK2 (0.58) TK2TYMPALDH1A1LMNAALB
SCHEMBL15691496 0.91 TK2 (0.58) TK2TYMPALDH1A1LMNAALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6586184-B2 Rearranging target nucleotide sequences; obtain cells, transfor with nucleotide sequences, detecting nucleotide sequences adjustment in prokaryotic cell VALIGEN (U.S.), INC. 2003-07-01 US claimed
US-20020151072-A1 Chimeric mutational vectors VALIGEN (U.S), INC. 2002-10-17 US claimed
EP-1078097-A4 CELL-FREE CHIMERAPLASTY AND EUKARYOTIC USE OF HETERODUPLEX MUTATIONAL VECTORS KIMERAGEN INC (US) 2002-06-05 EP claimed
EP-1084272-A4 HETERODUPLEX MUTATIONAL VECTORS AND USE THEREOF IN BACTERIA KIMERAGEN INC (US) 2002-03-13 EP claimed
US-6211351-B1 FOR INTRODUCTION OF GENETIC CHANGES IN EUKARYOTIC CELLS VALIGEN (US), INC. 2001-04-03 US claimed
EP-1084272-A1 HETERODUPLEX MUTATIONAL VECTORS AND USE THEREOF IN BACTERIA Kimeragen Inc. (US) 2001-03-21 EP claimed
EP-1078097-A1 CELL-FREE CHIMERAPLASTY AND EUKARYOTIC USE OF HETERODUPLEX MUTATIONAL VECTORS Kimeragen Inc. (US) 2001-02-28 EP claimed
US-6010907-A TRANSFORMING TARGET DNA SEQUENCES KIMERAGEN, INC. (US) 2000-01-04 US claimed
US-6004804-A 3'-EXONUCLEASE PROTECTED DUPLEX MUTATIONAL VECTORS; USED TO MAKE SPECIFIC GENETIC ALTERATIONS IN THE GENOME AND IN PLASMIDS OF TARGET PROKARYOTIC CELLS KIMERAGEN, INC. (US) 1999-12-21 US claimed
WO-1999058702-A1 CELL-FREE CHIMERAPLASTY AND EUKARYOTIC USE OF HETERODUPLEX MUTATIONAL VECTORS KIMERAGEN, INC. (US) 1999-11-18 WO claimed
WO-1999058723-A1 HETERODUPLEX MUTATIONAL VECTORS AND USE THEREOF IN BACTERIA KIMERAGEN, INC. (US) 1999-11-18 WO claimed