SCHEMBL20875717

SCHEMBL20875717

CO[Si](C)(CCCP(=O)(O)O)OC

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TYMS P04818 1/20 0.46
LPAR3 Q9UBY5 3/20 0.41
LPAR2 Q9HBW0 1/20 0.41
BBOX1 O75936 2/20 0.40
LMNA P02545 1/20 0.39
CYP3A4 P08684 1/20 0.39
NFKB1 P19838 1/20 0.39
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39
ALDH1A1 P00352 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
S1PR2 O95136 5/20 0.34
S1PR4 O95977 5/20 0.34
S1PR1 P21453 5/20 0.34
S1PR3 Q99500 5/20 0.34
S1PR5 Q9H228 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17678569 0.86 TYMS (0.38) TYMSLPAR3LPAR2BBOX1LMNA
SCHEMBL13789574 0.81 BHMT (0.34) TYMSLPAR3LPAR2
SCHEMBL7598369 0.80 TYMS (0.48) TYMSLPAR3LPAR2BBOX1LMNA
SCHEMBL20875719 0.79 LPAR3 (0.43) TYMSLPAR3LPAR2BBOX1LMNA
Hydrochloric Acid SCHEMBL10410977 0.78 TYMS (0.46) TYMSLPAR3LPAR2BBOX1LMNA
SCHEMBL28289622 0.76 LPAR3 (0.45) TYMSLPAR3LPAR2BBOX1LMNA
SCHEMBL13038574 0.76 LPAR3 (0.41) TYMSLPAR3LPAR2BBOX1LMNA
SCHEMBL2616664 0.74 LPAR3 (0.46) TYMSLPAR3LPAR2BBOX1LMNA
SCHEMBL28971492 0.74 PPARD (0.45) TDP1
SCHEMBL646421 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10844143-B2 Modified rubber containing silicon and phosphorus, composition and manufacturing method thereof TSRC CORPORATION (TW) 2020-11-24 US disclosed
EP-3470438-B1 MODIFIED RUBBER CONTAINING SI AND P, COMPOSITION AND MANUFACTURING METHOD THEREOF TSRC CORP (TW) 2020-05-13 EP disclosed
EP-3470438-A1 MODIFIED RUBBER CONTAINING SI AND P, COMPOSITION AND MANUFACTURING METHOD THEREOF TSRC Corporation (TW) 2019-04-17 EP disclosed
US-20190106511-A1 MODIFIED RUBBER CONTAINING SILICON AND PHOSPHORUS, COMPOSITION AND MANUFACTURING METHOD THEREOF TSRC CORPORATION (TW) 2019-04-11 US disclosed