Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.48 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 2/20 | 0.44 |
| ▸ | CPB1 | P15086 | 1/20 | 0.44 |
| ▸ | CPA3 | P15088 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9305402 | 0.86 | TDP1 (0.52) | TDP1GABBR2GABBR1LMNAMAPK1 | |
| SCHEMBL27559595 | 0.82 | LMNA (0.50) | LMNAMAPK1CYP2D6SRCMAPT | |
| SCHEMBL3965853 | 0.80 | KMT2A (0.53) | GABBR2GABBR1LMNAMAPK1MAPT | |
| SCHEMBL27473187 | 0.80 | SLC6A2 (0.55) | GABBR2GABBR1LMNAMAPK1CYP2D6 | |
| SCHEMBL687445 | 0.80 | LMNA (0.52) | LMNAMAPK1CYP2D6SRCMAPT | |
| SCHEMBL7056950 | 0.80 | LMNA (0.52) | LMNAMAPK1CYP2D6SRCMAPT | |
| SCHEMBL2387431 | 0.80 | CYP2D6 (0.61) | TDP1GABBR2GABBR1LMNAMAPK1 | |
| SCHEMBL295743 | 0.80 | LMNA (0.52) | LMNAMAPK1CYP2D6SRCMAPT | |
| SCHEMBL9196225 | 0.78 | HTT (0.55) | TDP1GABBR2GABBR1CYP2D6 | |
| Hydrochloric Acid SCHEMBL8672779 | 0.77 | TDP1 (0.46) | TDP1GABBR2GABBR1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3691624-A1 | COMPOUNDS FOR THE PREVENTION AND TREATMENT OF GLUCOSE INTOLERANCE RELATED CONDITIONS AND OBESITY. | Sorbonne Université (FR) | 2020-08-12 | — | — | EP | disclosed |
| WO-2019068788-A1 | COMPOUNDS FOR THE PREVENTION AND TREATMENT OF GLUCOSE INTOLERANCE RELATED CONDITIONS AND OBESITY. | Sorbonne Université (FR) | 2019-04-11 | — | — | WO | disclosed |