SCHEMBL20876151

SCHEMBL20876151

C[CH]C(C)n1ncc2ccccc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.39
RAB9A P51151 3/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
KDM4E B2RXH2 2/20 0.37
ALDH1A1 P00352 2/20 0.37
TP53 P04637 2/20 0.37
GAA P10253 2/20 0.37
HPGD P15428 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
HSD17B10 Q99714 2/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
CASP1 P29466 1/20 0.37
CASP7 P55210 1/20 0.37
ELANE P08246 1/20 0.37
CYP1A2 P05177 1/20 0.36
NPC1 O15118 2/20 0.35
KMO O15229 2/20 0.35
GLA P06280 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22285775 0.84 ELANE (0.39) RECQLRAB9AMEN1KMT2AKDM4E
SCHEMBL878425 0.81 RECQL (0.43) RECQLRAB9AMEN1KMT2AKDM4E
SCHEMBL29350890 0.81 RECQL (0.43) RECQLRAB9AMEN1KMT2AKDM4E
SCHEMBL21276545 0.78 RECQL (0.41) RECQLRAB9AMEN1KMT2AKDM4E
SCHEMBL20622947 0.78 RECQL (0.41) RECQLRAB9AMEN1KMT2AKDM4E
SCHEMBL29311539 0.78 RECQL (0.41) RECQLRAB9AMEN1KMT2AKDM4E
SCHEMBL6281573 0.75 ELANE (0.40) RECQLRAB9AMEN1KMT2AKDM4E
SCHEMBL3862440 0.75 RECQL (0.42) RECQLRAB9AMEN1KMT2AKDM4E
SCHEMBL30918021 0.75 MEN1 (0.44) RECQLRAB9AMEN1KMT2AKDM4E
SCHEMBL14722845 0.75 RECQL (0.39) RECQLRAB9AMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220167615-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2022-06-02 US claimed
CN-113966171-A Fungicidal compositions 先正达农作物保护股份公司 2022-01-21 CN claimed
WO-2024018016-A1 CRYSTALLINE FORMS OF 1,2,4-OXADIAZOLE FUNGICIDES SYNGENTA CROP PROTECTION AG (CH) 2024-01-25 WO disclosed
US-11629138-B2 Microbiocidal picolinamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2023-04-18 US disclosed
EP-3692029-B1 MICROBIOCIDAL PICOLINAMIDE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2023-04-12 EP disclosed
CN-111194314-B Microbicidal pyridine amide derivative 先正达参股股份有限公司 2022-12-30 CN disclosed
US-20220167615-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2022-06-02 US disclosed
EP-3952652-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2022-02-16 EP disclosed
CN-113966171-A Fungicidal compositions 先正达农作物保护股份公司 2022-01-21 CN disclosed
WO-2020208096-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2020-10-15 WO disclosed
US-20200255400-A1 Microbiocidal Picolinamide Derivatives SYNGENTA PARTICIPATIONS AG (CH) 2020-08-13 US disclosed
EP-3692029-A1 MICROBIOCIDAL PICOLINAMIDE DERIVATIVES Syngenta Participations AG (CH) 2020-08-12 EP disclosed
CN-111194314-A Microbicidal picolinamide derivatives 先正达参股股份有限公司 2020-05-22 CN disclosed
WO-2019068809-A1 MICROBIOCIDAL PICOLINAMIDE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2019-04-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200255400-A1 Microbiocidal Picolinamide Derivatives PRF1, CASP1, FPR1 RECQL 3778/4885RAB9A 2316/4885MEN1 3561/4885
US-11629138-B2 Microbiocidal picolinamide derivatives PRF1, CASP1, FPR1 RECQL 3778/4885RAB9A 2316/4885MEN1 3561/4885
US-20220167615-A1 FUNGICIDAL COMPOSITIONS CYP51A1, CYP4X1, CYP1B1 RECQL 2119/4885RAB9A 3970/4885MEN1 1547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.