Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.32 |
| ▸ | CHRNG | P07510 | 1/20 | 0.32 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CHRND | Q07001 | 1/20 | 0.32 |
| ▸ | LIG1 | P18858 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1836883 | 0.77 | MAOB (0.39) | SLC6A3SLC6A4SLC6A2MAOBMAOA | |
| SCHEMBL498413 | 0.76 | OPRL1 (0.50) | MAOBMAOAOPRM1 | |
| SCHEMBL7241994 | 0.76 | MAOB (0.38) | SLC6A3SLC6A4SLC6A2MAOBMAOA | |
| SCHEMBL15043629 | 0.75 | SLC6A3 (0.42) | SLC6A3SLC6A4SLC6A2MAOBMAOA | |
| SCHEMBL15043624 | 0.74 | SLC6A3 (0.45) | SLC6A3SLC6A4SLC6A2MAOBMAOA | |
| SCHEMBL8676816 | 0.74 | SLC6A3 (0.34) | SLC6A3SLC6A4SLC6A2MAOBMAOA | |
| SCHEMBL15043707 | 0.70 | SLC6A3 (0.45) | SLC6A3SLC6A4SLC6A2HSD11B1OPRM1 | |
| SCHEMBL8530637 | 0.69 | SLC6A3 (0.36) | SLC6A3SLC6A4SLC6A2MAOBMAOA | |
| SCHEMBL8530639 | 0.69 | SLC6A3 (0.36) | SLC6A3SLC6A4SLC6A2MAOBMAOA | |
| SCHEMBL9230998 | 0.69 | MAOB (0.43) | SLC6A3SLC6A4SLC6A2MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3692019-A1 | MICROBIOCIDAL PICOLINAMIDE DERIVATIVES | Syngenta Participations AG (CH) | 2020-08-12 | — | — | EP | disclosed |
| CN-111183133-A | Microbicidal picolinamide derivatives | 先正达参股股份有限公司 | 2020-05-19 | — | — | CN | disclosed |
| WO-2019068812-A1 | MICROBIOCIDAL PICOLINAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-04-11 | — | — | WO | disclosed |