Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8530637 | 1.00 | SLC6A3 (0.36) | SLC6A3HSD11B1SLC6A4SLC6A2OPRM1 | |
| SCHEMBL8532110 | 0.84 | DRD2 (0.36) | SLC6A3HSD11B1SLC6A4SLC6A2OPRM1 | |
| SCHEMBL7918506 | 0.84 | DRD2 (0.36) | SLC6A3HSD11B1SLC6A4SLC6A2OPRM1 | |
| SCHEMBL7918509 | 0.84 | DRD2 (0.36) | SLC6A3HSD11B1SLC6A4SLC6A2OPRM1 | |
| SCHEMBL8534276 | 0.78 | SLC6A4 (0.44) | HSD11B1SLC6A4APPCYP3A4CYP2C9 | |
| SCHEMBL8531546 | 0.78 | NQO1 (0.41) | MEN1KMT2A | |
| SCHEMBL8531488 | 0.78 | SLC6A4 (0.44) | SLC6A3SLC6A4SLC6A2MAOBMEN1 | |
| SCHEMBL8531549 | 0.78 | NQO1 (0.41) | MEN1KMT2A | |
| SCHEMBL8531485 | 0.78 | SLC6A4 (0.44) | SLC6A3SLC6A4SLC6A2MAOBMEN1 | |
| SCHEMBL8534274 | 0.78 | SLC6A4 (0.44) | HSD11B1SLC6A4APPCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763700-A | INSECTICIDES | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1998-06-09 | — | — | US | disclosed |
| EP-0660815-B1 | PESTICIDAL FLUOROOLEFINS | BRITISH TECH GROUP (GB) | 1997-04-16 | — | — | EP | disclosed |
| EP-0660815-A1 | PESTICIDAL FLUOROOLEFINS. | BRITISH TECNOLOGY GROUP PLC (GB) | 1995-07-05 | — | — | EP | disclosed |
| WO-1994006741-A1 | PESTICIDAL FLUOROOLEFINS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1994-03-31 | — | — | WO | disclosed |