Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 10/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.36 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20877660 | 1.00 | CES1 (0.41) | CES1TTRBCHETGM2CASP3 | |
| SCHEMBL20877618 | 0.82 | CASP3 (0.41) | CASP3ALDH1A1GAANPSR1 | |
| SCHEMBL20877620 | 0.82 | CASP3 (0.41) | CASP3ALDH1A1GAANPSR1 | |
| SCHEMBL28362284 | 0.74 | CES1 (0.44) | CES1TTRBCHETGM2CASP3 | |
| SCHEMBL4803383 | 0.74 | CES1 (0.53) | CES1TTRBCHETGM2CASP3 | |
| SCHEMBL18281472 | 0.70 | CES1 (0.57) | CES1TTRBCHETGM2CASP3 | |
| SCHEMBL4199767 | 0.70 | CES1 (0.57) | CES1TTRBCHETGM2CASP3 | |
| SCHEMBL19924174 | 0.69 | CES1 (0.50) | CES1TTRBCHETGM2CASP3 | |
| Hydrochloric Acid SCHEMBL29591677 | 0.68 | CES1 (0.55) | CES1TTRBCHETGM2CASP3 | |
| SCHEMBL281336 | 0.67 | CES1 (0.50) | CES1TTRBCHETGM2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10752625-B2 | Method of making tetrahydronaphthyridinyl nonanoic acid compounds | SCIFLUOR LIFE SCIENCES, INC. (US) | 2020-08-25 | — | — | US | disclosed |
| US-20190194195-A1 | METHOD OF MAKING TETRAHYDRONAPHTHYRIDINYL NONANOIC ACID COMPOUNDS | FELIQS CORPORATION (JP) | 2019-06-27 | — | — | US | disclosed |
| US-10253025-B2 | Method of making tetrahydronaphthyridinyl nonanoic acid compounds | SCIFLUOR LIFE SCIENCES, INC. (US) | 2019-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190194195-A1 | METHOD OF MAKING TETRAHYDRONAPHTHYRIDINYL NONANOIC ACID COMPOUNDS | NISCH, SLC10A1, AANAT | CES1 382/4885TTR 448/4885BCHE 357/4885 |
| US-10752625-B2 | Method of making tetrahydronaphthyridinyl nonanoic acid compounds | NISCH, SLC10A1, AANAT | CES1 382/4885TTR 448/4885BCHE 357/4885 |
| US-10253025-B2 | Method of making tetrahydronaphthyridinyl nonanoic acid compounds | NISCH, SLC10A1, AANAT | CES1 382/4885TTR 448/4885BCHE 357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.