Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21107981 | 1.00 | MAPK1 (0.41) | MAPK1HPGDTSHRUSP2IDO1 | |
| SCHEMBL20877672 | 1.00 | MAPK1 (0.41) | MAPK1HPGDTSHRUSP2IDO1 | |
| SCHEMBL2154257 | 0.77 | MAPK1 (0.45) | MAPK1HPGDTSHRUSP2IDO1 | |
| SCHEMBL4552083 | 0.77 | MAPK1 (0.45) | MAPK1HPGDTSHRUSP2IDO1 | |
| SCHEMBL5503209 | 0.73 | IDO1 (0.50) | MAPK1HPGDTSHRUSP2IDO1 | |
| SCHEMBL5503210 | 0.73 | IDO1 (0.50) | MAPK1HPGDTSHRUSP2IDO1 | |
| SCHEMBL27363652 | 0.71 | MAPK1 (0.49) | MAPK1HPGDTSHRUSP2IDO1 | |
| SCHEMBL29591678 | 0.71 | MAPK1 (0.52) | MAPK1HPGDTSHRUSP2IDO1 | |
| SCHEMBL2600306 | 0.71 | MAPK1 (0.52) | MAPK1HPGDTSHRUSP2IDO1 | |
| SCHEMBL20812687 | 0.68 | MAPK1 (0.49) | MAPK1HPGDTSHRUSP2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10752625-B2 | Method of making tetrahydronaphthyridinyl nonanoic acid compounds | SCIFLUOR LIFE SCIENCES, INC. (US) | 2020-08-25 | — | — | US | disclosed |
| US-20190194195-A1 | METHOD OF MAKING TETRAHYDRONAPHTHYRIDINYL NONANOIC ACID COMPOUNDS | FELIQS CORPORATION (JP) | 2019-06-27 | — | — | US | disclosed |
| US-10253025-B2 | Method of making tetrahydronaphthyridinyl nonanoic acid compounds | SCIFLUOR LIFE SCIENCES, INC. (US) | 2019-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190194195-A1 | METHOD OF MAKING TETRAHYDRONAPHTHYRIDINYL NONANOIC ACID COMPOUNDS | NISCH, SLC10A1, AANAT | MAPK1 3846/4885HPGD 229/4885TSHR 441/4885 |
| US-10752625-B2 | Method of making tetrahydronaphthyridinyl nonanoic acid compounds | NISCH, SLC10A1, AANAT | MAPK1 3846/4885HPGD 229/4885TSHR 441/4885 |
| US-10253025-B2 | Method of making tetrahydronaphthyridinyl nonanoic acid compounds | NISCH, SLC10A1, AANAT | MAPK1 3846/4885HPGD 229/4885TSHR 441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.